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How cancer cells rewire their metabolism to survive -- ScienceDaily

www.sciencedaily.com/releases/2013/01/130131144427.htm

Jan 31, 2013 ... Many scientists have tried killing tumors by taking away their favorite food, a sugar called glucose. Unfortunately, this treatment approach not ...

Oral cancer cells may rewire alternative metabolic pathways ... - NCBI

www.ncbi.nlm.nih.gov/pubmed/24666435

Mar 25, 2014 ... Oral cancer cells may rewire alternative metabolic pathways to survive from siRNA ... BACKGROUND: Cancer cells may undergo metabolic adaptations that ... to knock down their expression of important metabolic enzymes.

Cancer Metabolism - Agios

www.agios.com/science-cancer-metabolism.php

The metabolic rewiring of cancer cells can also be linked to specific genetic ... Cancer cells alter their consumption and the way they process sugars, fats, amino ...

The Warburg Effect: How Does it Benefit Cancer Cells?

jlocasale.duke.edu/uploads/1/3/2/8/13288106/tibs_the_warburg_effect_2016.pdf

Cancer cells rewire their metabolism to promote growth, survival, proliferation, ... for the[17_TD$DIFF] function of Warburg Effect, emphasize their rationale, and ...

Cell Death and Disease - Gluconeogenesis combats cancer ...

www.nature.com/cddis/journal/v6/n9/full/cddis2015245a.html

Sep 3, 2015 ... Metabolic reprogramming, now considered a hallmark of cancer, has become a major ... evidence of rewiring of glucose metabolism in cancer cells. ... and its consequences in proliferation and survival of human cancer cells.

Is Cancer a Metabolic Disease? - ScienceDirect

www.sciencedirect.com/science/article/pii/S0002944013006536

Oct 17, 2013 ... Growing tumors rewire their metabolic programs to meet and even exceed the ... also correlate with shorter survival and increased metastases in cervical ... In this review, we consider the way in which cancer cells rewire their ...

Metabolism 'rewiring' can lead to aggressive lung cancer - News ...

www.mrc.ac.uk/news/browse/metabolism-rewiring-can-lead-to-aggressive-lung-cancer/

Feb 24, 2016 ... Metabolism 'rewiring' can lead to aggressive lung cancer ... 'rewire' their energy supply, helping them to survive and making them more likely to spread. ... Lung cancer cells with extra copies of Kras mutations increase their ...

Rewiring Metabolism Slows Cancer Growth

healthcare.utah.edu/publicaffairs/news/2014/10/10-30-14-Rewiring-Metabolism-Slows-Cancer-Growth.php

Oct 30, 2014 ... As the disease advances, tumor cells accumulate mutations, ... “Loss of MPC seems to be a biomarker for cancer aggressiveness and patient survival,” ... noted that cancer cells change their metabolism, a mechanism later ...

Nutrient deprivation kills kidney cancer cells - Medical Xpress

medicalxpress.com/news/2016-02-nutrient-deprivation-kidney-cancer-cells.html

Feb 3, 2016 ... As a result, cancer cells must alter their metabolism to provide the additional fuel needed for them to survive, grow and ... 1, 2016 in Cancer Research shows that the majority of these cancers rewire their metabolism in a way ...

Researchers identify control mechanism for glutamine uptake in ...

medicalxpress.com/news/2015-03-mechanism-glutamine-uptake-breast-cancer.html

Mar 10, 2015 ... "Using a cohort of more than 500 breast cancer patient samples, we ... Explore further: How cancer cells rewire their metabolism to survive.

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Oral cancer cells may rewire alternative metabolic ... - BMC Cancer

bmccancer.biomedcentral.com

Oral cancer cells may rewire alternative metabolic pathways to survive from siRNA ... (siRNA) to knock down their expression of important metabolic enzymes .

Links between metabolism and cancer - Genes & Development

genesdev.cshlp.org

Hypoxic adaptation by cancer cells is essential for survival and progression of a tumor. ... hypoxic cells shunt glucose to lactate and rewire glutamine metabolism. ... cancer cells may profoundly influence their responses to metabolic stresses, ...

Metabolic liabilities of cancer cells to the tumor nutrient environment ...

grantome.com

It has recently become evident that cancer cells rewire their metabolism to meet their demands of proliferation and survival. Metabolic changes are dictated in...