Jan 31, 2013 ... Many scientists have tried killing tumors by taking away their favorite food, a
sugar called glucose. Unfortunately, this treatment approach not ...
Growing tumors rewire their metabolic programs to meet and even exceed the ...
Tumor-produced lactate concentrations also correlate with shorter survival and ...
Is the metabolic phenotype of cancer cells a reflection of their rapid growth?
Cancer cells are well documented to rewire their metabolism and energy .... In
addition, G6PD also promotes cancer survival by producing NADPH, a key tool
The metabolic rewiring of cancer cells can also be linked to specific genetic ...
Cancer cells alter their consumption and the way they process sugars, fats,
Feb 28, 2013 ... ... as well as the rewiring of cellular signalling and the reprogramming of
metabolic pathways. ... From its metabolism to pyruvate, glutamine is key for
providing reduced ... Figure 2 | Effect of FAO on cancer cell metabolism, growth
and survival. ... But there are situations in which cancer cells seem to require ...
Metabolic pathways promoting cancer cell survival and growth on ... approaches
to probe tumour metabolism in vivo and their potential to expand the metabolic ....
survive cancer cells during energy stress through rewiring cancer metabolism.
Hypoxic adaptation by cancer cells is essential for survival and progression of a
tumor. ... hypoxic cells shunt glucose to lactate and rewire glutamine metabolism.
... cancer cells may profoundly influence their responses to metabolic stresses, ...
tation in surviving tumor cells in order to cope with challenging conditions. This
metabolic ... rewire their metabolism in order to survive. Although a large.
Sep 3, 2015 ... Metabolic reprogramming, now considered a hallmark of cancer, has become a
major ... evidence of rewiring of glucose metabolism in cancer cells. ... and its
consequences in proliferation and survival of human cancer cells.
Feb 24, 2016 ... Metabolism 'rewiring' can lead to aggressive lung cancer ... 'rewire' their energy
supply, helping them to survive and making them more likely to spread. ... Lung
cancer cells with extra copies of Kras mutations increase their ...