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How cancer cells rewire their metabolism to survive -- ScienceDaily

www.sciencedaily.com/releases/2013/01/130131144427.htm

Jan 31, 2013 ... Many scientists have tried killing tumors by taking away their favorite food, a sugar called glucose. Unfortunately, this treatment approach not ...

Is Cancer a Metabolic Disease? - NCBI - National Institutes of Health

www.ncbi.nlm.nih.gov/pmc/articles/PMC3873478/

Growing tumors rewire their metabolic programs to meet and even exceed the ... shorter survival and increased metastases in cervical and head and neck cancer. ... Is the metabolic phenotype of cancer cells a reflection of their rapid growth?

Cancer metabolic reprogramming: importance, main features, and ...

www.ncbi.nlm.nih.gov/pmc/articles/PMC3969803/

Cancer cells are well documented to rewire their metabolism and energy .... In addition, G6PD also promotes cancer survival by producing NADPH, a key tool for ...

Cancer Metabolism - Agios

www.agios.com/science-cancer-metabolism.php

The metabolic rewiring of cancer cells can also be linked to specific genetic ... Cancer cells alter their consumption and the way they process sugars, fats, amino ...

Hacking Cancer Metabolism - Cell

www.cell.com/cell-metabolism/pdf/S1550-4131(16)30552-6.pdf

Nov 8, 2016 ... lighted six emerging hallmarks of cancer metabolism, and while not all tumors ... blasts (CAFs) and tumor cells, showing that CAFs can rewire their ... to increase their survival and functionality during the anti-tumor response.

The Warburg Effect: How Does it Benefit Cancer Cells?

www.cell.com/trends/biochemical-sciences/pdf/S0968-0004(15)00241-8.pdf

Cancer cells rewire their metabolism to promote growth, survival, proliferation, ... for the function of Warburg Effect, emphasize their rationale, and discuss their.

Links between metabolism and cancer - Genes & Development

genesdev.cshlp.org/content/26/9/877.full

Hypoxic adaptation by cancer cells is essential for survival and progression of a tumor. ... hypoxic cells shunt glucose to lactate and rewire glutamine metabolism. ... cancer cells may profoundly influence their responses to metabolic stresses, ...

Tissue-specific and convergent metabolic transformation of cancer ...

www.nature.com/articles/ncomms13041

Oct 10, 2016 ... Cancer cells reprogramme their metabolism with unclear clinical implications. ... of cancer correlates with metastatic potential and patient survival ... We find that cancers undergo a tissue-specific metabolic rewiring, which ...

Metabolic rewiring of pancreatic ductal adenocarcinoma: New ...

onlinelibrary.wiley.com/doi/10.1002/ijc.29501/pdf

tation in surviving tumor cells in order to cope with challenging conditions. This metabolic ... rewire their metabolism in order to survive. Although a large.

mTORC1-Dependent Metabolic Reprogramming Underlies ... - Cell

www.cell.com/cancer-cell/pdf/S1535-6108(16)30052-6.pdf

Mar 24, 2016 ... Glycolysis-addicted cancer cells metabolically rewire to escape glucose ... and mTORC1 signaling disrupted metabolic reprogramming in tumor cells and inhibited their growth .... (G) 2DG survival curves for GD and GI lines.

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Oral cancer cells may rewire alternative metabolic ... - BMC Cancer

bmccancer.biomedcentral.com

Oral cancer cells may rewire alternative metabolic pathways to survive from ... Cancer cells may undergo metabolic adaptations that support their growth as well ...

The Warburg Effect: How Does it Benefit Cancer Cells? - NCBI

www.ncbi.nlm.nih.gov

Jan 5, 2016 ... (2)Department of Pharmacology and Cancer Biology, Duke University ... Cancer cells rewire their metabolism to promote growth, survival, ...

Oral cancer cells may rewire alternative metabolic pathways ... - NCBI

www.ncbi.nlm.nih.gov

Mar 25, 2014 ... Oral cancer cells may rewire alternative metabolic pathways to survive from siRNA ... BACKGROUND: Cancer cells may undergo metabolic adaptations that ... to knock down their expression of important metabolic enzymes.