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Triclosan

en.wikipedia.org/wiki/Triclosan

Triclosan, similar in its uses and mechanism of action to triclocarban, is an antibacterial and antifungal agent found in consumer products, including toothpaste, soaps, detergents, toys, and surgic...

Mechanism of Triclosan Inhibition of Bacterial Fatty Acid Synthesis

www.jbc.org/content/274/16/11110.full

Apr 16, 1999 ... Mechanism of Triclosan Inhibition of Bacterial Fatty Acid Synthesis* ... In contrast, triclosan does not increase the binding of NAD<sup>+</sup>to FabI[G93V]. ... The importance of fatty acid biosynthesis to cell growth and function makes ...

1. What is the biocide triclosan?

ec.europa.eu/health/scientific_committees/opinions_layman/triclosan/en/l-3/1-biocides.htm

At sublethal concentrations, it acts by inhibiting the activity of the bacterial .... triclosan was found to profoundly affect bacterial growth, indicating a strong ...

Triclosan and Antibiotics resistance

ec.europa.eu/health/scientific_committees/opinions_layman/triclosan/en/

... such as cosmetics and detergents to kill microorganisms or inhibit their growth. ... 3.3 If present in soil, triclosan does not seem to affect bacterial activity, but it ...

The Effects of Triclosan Derivatives against the Growth of ...

digitalcommons.liberty.edu/cgi/viewcontent.cgi?article=1027&context=honors

of triclosan did not have high inhibition rates at 4.0 ug/mL, but more .... inhibits bacterial fatty acid synthesis and thus inhibits bacteria growth by disrupting.

Triclosan - Tufts University

emerald.tufts.edu/med/apua/consumers/personal_home_21_4240495089.pdf

inhibits the enzyme, and therefore prevents the bacteria from synthesizing fatty acid, which is ... Since humans do not have this ENR enzyme, triclosan ... Microban® controls microbial growth and odors within the impregnated surface but does ...

General Background: Antibiotic Agents - Tufts

emerald.tufts.edu/med/apua/about_issue/agents.shtml

Do antibacterials create resistant bacteria? Can the widespread use of ... Bacteriostats inhibit bacterial growth in inanimate environments. Sanitizers are ...

Triclosan and antimicrobial resistance in bacteria: an overview. - NCBI

www.ncbi.nlm.nih.gov/pubmed/16922622

Microb Drug Resist. 2006 Summer;12(2):83-90. Triclosan and antimicrobial resistance in bacteria: an overview. Yazdankhah SP(1), Scheie AA, Høiby EA, ...

Triclosan inhibition of fatty acid synthesis and its effect on growth of ...

www.ncbi.nlm.nih.gov/pubmed/15860550

Apr 28, 2005 ... Triclosan inhibition of fatty acid synthesis and its effect on growth of Escherichia ... and to relate the inhibition of enoyl reductase to bacterial viability. ... These concentrations did not significantly affect cell survival in any of the ...

Antibacterial Household Products: Cause for Concern - NCBI

www.ncbi.nlm.nih.gov/pmc/articles/PMC2631814/pdf/11485643.pdf

used correctly, they inhibit bacterial growth. ... triclosan (a common antibacterial agent), including pillows, .... A triclosan-resistant mutant of E. coli does not lyse.

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Full Text - Journal of Antimicrobial Chemotherapy - Oxford Journals

jac.oxfordjournals.org

Apr 28, 2005 ... Triclosan inhibition of fatty acid synthesis and its effect on growth of ... Concurrently, the bactericidal effect of triclosan against these bacterial strains was ... These concentrations did not significantly affect cell survival in any of ...

Illumin - What Makes Antibacterial Soap Antibacterial?

illumin.usc.edu

Dec 1, 2007 ... A biochemical explanation of how Triclosan disables bacteria will give ... with Triclosan, consumers should consider antibacterial products that do not use ... Triclosan stops the fatty acid elongation process by inhibiting a bacterial enzyme. ... systematically kills bacteria by stopping fatty acid chain growth.

Defining and Combating the Mechanisms of Triclosan Resistance in ...

aac.asm.org

Consequently, the measured IC50s do not truly reflect the relative affinities of triclosan for the .... Mechanism of triclosan inhibition of bacterial fatty acid synthesis.