Web Results

Patent WO2014145035A1 - Methods of making cancer compositions ...


Sep 18, 2014 ... Applicant, Genspera, Inc. ... and (d) reacting the compound of Formula 6 with the compound of ..... Sci., USA 1996;93:749- 753; Mhaka, A., et al, Cancer Biol Ther. ... by PSMA in vitro and is ~ 60-fold more toxic to PSMA expressing vs. ..... with 1.0 L of 6 M HC1 over 30 minutes (pH~3) a white slurry develops.

Tasquinimod Is an Allosteric Modulator of HDAC4 Survival Signaling ...


Feb 15, 2013 ... D, TasQ dose–response inhibition of 3D EC sprouting in fibrin gels over a 7-day ... Reagents: G202 (GenSpera); Tasquinimod (Active Biotech ..... CO2 and decreasing pH, 60% knockdown of HDAC4 decreases survival ..... Denmeade SR,; Mhaka AM,; Rosen DM,; Brennen WN,; Dalrymple S,; Dach I,; et al.

Tasquinimod Is an Allosteric Modulator of ... - Cancer Research


Feb 15, 2013 ... Reagents: G202 (GenSpera); Tasquinimod (Active Biotech ... HDAC4 specific substrate; Bachem Inc.). ... Tris HCl pH 7.4 with 150 mmol/L NaCl/1% Triton and protease ... Isaacs et al. .... 4.8 Æ 0.9% of tumor area in TasQ treated vs. ... untreated control cells. D, TasQ dose-response inhibition of 3D EC.

Popular Q&A
Q: When will i get my benefits? white, et al. v. experian informatio...
A: If you submitted a claim for one or more of the benefits provided by this Settlement, you will be notified about how and when you can obtain these benefits afte... Read More »
Source: www.bankruptcydischargesettlement.com
Q: What is the replaytv case about? newmark, et al., v. turner broad...
A: In 2001, 28 major movie studios, television networks, and cable companies sued the creator of an innovative new digital video recorder (DVR) that allows you to ... Read More »
Source: www.eff.org
Q: What is the lawsuit about? caissie, et al. v. bj’s wholesale club...
A: A former mid-manager of BJ's Wholesale Club, Inc. filed a lawsuit against BJ’s alleging that he should have been classified as a non-exempt employee and that he... Read More »
Source: www.midmanagerssettlement.com
Helpful Resources

Engineering a Prostate-Specific Membrane Antigen–Activated ...


Jun 27, 2012 ... 1, D and E). ..... Purified G202 for animal studies was provided by GenSpera Inc. PSMA ... of Milowsky et al. with a PSMA antibody (clone 3E6; Dako) diluted 1:20 in .... The role of calcium, pH, and cell proliferation in the programmed .... Singh P, Mhaka AM, Christensen SB, Gray JJ, Denmeade SR, Isaacs JT.

Amino acid containing thapsigargin analogues deplete androgen ...


May 5, 2009 ... There are quantitative and/or qualitative mechanisms al- ..... fragmentation into Annexin V–positive apoptotic bodies .... D, XBP-1 processing in LNCaP prostate cancer cells treated with .... J.T. Isaacs and S.R. Denmeade: financial interest, Genspera, Inc., and .... Singh P, Mhaka AM, Christensen SB, et al.