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Nav1.4 - Wikipedia


Sodium channel protein type 4 subunit alpha is a protein that in humans is encoded by the SCN4A gene. The Nav1.4 voltage-gated sodium channel is encoded ...

Engineering Highly Potent and Selective Microproteins against ...


Jul 1, 2016 ... ... Bristol-Myers Squibb, 700 Bay Rd., Redwood City, CA 94063. ... The resulting microproteins are highly potent (IC50 to Nav1.7 of 2.5 nm) and selective. ... (Nav1 .4) and cardiac (Nav1.5) sodium channels is above 3000 nm.

Brandon M. Brown | LinkedIn


University of California, Davis ... January 2016 – Present (9 months)San Francisco Bay Area .... selective over representative KV (KV1.3, KV2.1, KV3.1, and KV11.1), NaV (NaV1.2, NaV1.4, NaV1.5, and NaV1.7), as well as CaV1.2 channels.

City of Redwood City : Home


Skip to page body Home About the City City Hall Departments Residents Business I Want to... Home Menu. Calendar .... Apply for a Job · 4 Get a Permit · 5 ... Redwood City Parking Initiatives and Transportation Management Update ( blog).

Molecular Pain (2014) - Fasteris


Mar 11, 2014 ... All isoforms, except Nav1.4 ... Nav1.8 and Nav1.9—were also highly expressed in mouse ..... (11.0, Sun Microsystems, Redwood City, CA).

ML297 (VU0456810), the First Potent and Selective Activator of the ...


Jun 3, 2013 ... AfaSci Research Laboratory, Redwood City, California 94063, United States. ACS Chem. Neurosci. , 2013, 4 (9), pp 1278–1286 ... for the Sodium Channel NaV1.7 and Its Utility for Lead Discovery and Compound Profiling.

Jieying Luo - Google Scholar Citations


Molecular surface of JZTX-V (β-Theraphotoxin-Cj2a) interacting with voltage- gated sodium channel subtype NaV1. 4. J Luo, Y Zhang, M Gong, S Lu, Y Ma, ...

Dynamic Changes in the MicroRNA Expression Profile Reveal ...


Mar 14, 2011 ... We performed a miRNA expression profiling study of DRG 4 weeks following ... For our studies we chose Cacna2d1, Scn11A or Nav1.9, and P2rx4, each of ..... Redwood City, CA) and MetaCore (GeneGo; www.genego.com).

Identification of a novel contactin‐associated transmembrane ...


Mar 1, 1997 ... Abstract. Receptor protein tyrosine phosphatase β expressed on the surface of glial cells binds to the glycosylphosphatidylinositol ...

A gene network downstream of transcription factor Math5 regulates ...


Data analysis was performed with GeneSpring 6.1 (Silicon Genetics, Redwood City, CA). ... Briefly, E14.5 embryos were fixed with 4% paraformaldehyde, washed three times ..... NM_173437⁎, Nav1, neuron navigator 1, 0.94, 0.52, 0.89 , 0.76.

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Physiological and Pathophysiological Insights of Nav1.4 and Nav1.5 ...


Jan 14, 2016 ... Mutations in Nav1.4 and Nav1.5 α-subunits have been associated ... Main classes of Nav1.4 skeletal muscle channelopathies (Trip et al., ...... Bezzina C. R., Barc J., Mizusawa Y., Remme C. A., Gourraud J. B., Simonet F., et al.

Bristol-Myers Squibb Partnering Day - California Life Sciences ...


Mar 21, 2016 ... ... neurological diseases (tauopathies, synucleopathies, Nav1.7 small fiber neuropathies, ... 4:30pm — 6:30pm ... Redwood City, CA 94065.

Digital VOR - Davtron


427 HILLCREST WAY. REDWOOD CITY, CA 94062 ... The ident feature resets upon the selection of NAV1 or NAV2 signal input. In some of the new ... Page 4 ...