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Nav1.4 - Wikipedia


Sodium channel protein type 4 subunit alpha is a protein that in humans is encoded by the SCN4A gene. The Nav1.4 voltage-gated sodium channel is encoded ...

Physiological and Pathophysiological Insights of Nav1.4 and Nav1.5 ...


Jan 14, 2016 ... Mutations in Nav1.4 and Nav1.5 α-subunits have been associated ... Main classes of Nav1.4 skeletal muscle channelopathies (Trip et al., ...... Bezzina C. R., Barc J., Mizusawa Y., Remme C. A., Gourraud J. B., Simonet F., et al.

Defective Fast Inactivation Recovery of Nav1.4 in Congenital ... - NCBI


Mar 27, 2015 ... This study was approved by the institutional review board of the University of California, Davis. The patient and her family were informed of their ...

Download PDF - Sage Publications


Mar 11, 2014 ... All isoforms, except Nav1.4 ... Nav1.8 and Nav1.9—were also highly expressed in mouse ..... (11.0, Sun Microsystems, Redwood City, CA).

Bristol-Myers Squibb Partnering Day - California Life Sciences ...


Mar 21, 2016 ... ... neurological diseases (tauopathies, synucleopathies, Nav1.7 small fiber neuropathies, ... 4:30pm — 6:30pm ... Redwood City, CA 94065.

Dynamic Changes in the MicroRNA Expression Profile Reveal ... - Plos


Mar 14, 2011 ... We performed a miRNA expression profiling study of DRG 4 weeks following ... For our studies we chose Cacna2d1, Scn11A or Nav1.9, and P2rx4, each of ..... Redwood City, CA) and MetaCore (GeneGo; www.genego.com).

Digital VOR - Davtron


427 HILLCREST WAY. REDWOOD CITY, CA 94062 ... The ident feature resets upon the selection of NAV1 or NAV2 signal input. In some of the new ... Page 4 ...

Publications - Pasca Lab @ Stanford University


A deleterious NaV1.1 mutation selectively impairs telencephalic inhibitory neurons ... American Journal of Psychiatry, 173(4): 332-3, 2016. ... Miu A.C., Heilman R.M., Paşca S.P., Stefan C.A., Spanu F., Vasiu R., Olteanu A.I., and Miclea M.

ML297 (VU0456810), the First Potent and Selective Activator of the ...


Jun 3, 2013 ... AfaSci Research Laboratory, Redwood City, California 94063, United States. ACS Chem. Neurosci. , 2013, 4 (9), pp 1278–1286 ... for the Sodium Channel NaV1.7 and Its Utility for Lead Discovery and Compound Profiling.

2015 Medicines in Development for Neurological Disorders - PhRMA


South San Francisco, CA www.comentis. ..... (4-aminobutyrate transaminase inhibitor). Coral Gables ..... Redwood City, CA ..... (Nav1.7 sodium channel inhibitor).