Sep 16, 2014 ... Keywords: cancer, cell metabolism, drugs, metabolism modulating agents, ....
PKM2 dimers also act as transcriptional co-factors that promote .... with advanced
solid tumors; in 11 evaluable patients, one had PR and 6 had SD . ..... De
Lena M, Lorusso V, Latorre A, et al. ..... Han JY, Lim KY, Yu SY, et al.
TEL-JAK2 fusion types derived from both T-cell acute lymphoblastic leukemia
and .... After incubation at 37°C in 10% (v/v) CO2 for 2 days, a total cell lysate was
..... and Deakin University International Research Scholarship Scheme (SMNO,
PR, JK). ... Flex E, Petrangeli V, Stella L, Chiaretti S, Hornakova T, Knoops L, et al
Since Takeshige et al. carried out the first genetic screen for autophagy mutants,
... In the presence of Hsc73 and other Hsp70 co-chaperones, such as Hsp40,
Hsp90, ..... Copetti et al. demonstrated that the NF-κB family member p65/RelA (v-
rel ... and it is considered the first-line treatment for advanced renal cell
In previously treated, unselected, advanced NSCLC patients, the addition of ....
response (CR) or partial response (PR) (whichever status was recorded first) ...
former and current smokers (median PFS of 10.3 vs 1.6 months, respectively; P =
0.02). .... F. Dunphy, The TAX 320 Non-Small Cell Lung Cancer Study Group, et
Sep 25, 2016 ... Institute for Clean Energy and Advanced Materials, Faculty of Materials and ...
The NPs functionalized with HA are able to guide the co-delivery of drugs to the
..... (e) Cellular uptake profiles of HA-CUR-NPs in Colon-26 cells and Raw 264.7
..... Sun TM, Du JZ, Yao YD, Mao CQ, Dou S, Huang SY. et al.
<sup>1</sup>Génétique, Immunothérapie, Chimie et Cancer (GICC) UMR 7292, CNRS, ...
Using a rat model of an acute AML subtype, the promyelocytic leukemia, Jensen
et al. .... Conversely, HIF-2alpha triggers cell cycle progression and proliferation
by ... al. (122) discovered a translocation involving TEL and ARNT in an AML
... [CR], partial response [PR]) in patients with KRAS wild-type tumours (arms A
and B) and disease control (DC; CR, PR, ... tandem mass spectrometry method at
BI Pharma GmbH & Co. ..... In contrast with the results reported by Tejpar et al. ....
Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung
May 25, 2016 ... Methods In this review, we summarize recent advance in cancer research focus
... Epithelial-mesenchymal transition (EMT) is a crucial event for cell ... Ng et al. [
32] reported that TWIST1 induced N-cadherin to promote ... MicroRNA can
regulate carcinogenesis through affecting co-factors of EMT inducers.
Up to 40% of patients with diffuse large B-cell lymphoma (DLBCL) are not cured
... were not routinely performed except to confirm CR in patients with prolonged
PR. ... Each study arm had 90% power to detect a response rate of 30% vs 5%
using a ..... BCL6 expression, but this observation was not reproduced by Pon et
Telephone: +49-(0)6421-5866234 ... Recently, the heterogeneity in terms of
cellular and molecular pathways .... Viral infections are co-modulators of early
onset BA. Early .... marker for a TH2-driven immune-response, Woodruff et al. ...
different integrin molecules on the cell surface such as alpha-V/beta1, alpha-V/
beta3 and ...