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Cannabis use and driving: implications for public ... - Emcdda - Europa

www.emcdda.europa.eu/attachements.cfm/att_53399_EN_emcdda-cannabis-mon-vol2-ch9-web.pdf

Cannabis use and driving: implications for public health and transport policy. 174 ... or more may report DUIC at least once in the previous year (Albery et al., 1999; .... England and Wales. No. 2.6%. No. Fortenberry et al. (1986). Alabama, USA ...... accidents in Italy', in Perrine, M. (ed), Alcohol, drugs, and traffic safety — T'...

Orphan drugs for sickle vaso-occlusion: dawn of a new era of ...

www.dovepress.com/orphan-drugs-for-sickle-vaso-occlusion-dawn-of-a-new-era-of-targeted-t-peer-reviewed-fulltext-article-ODRR

Nov 2, 2015 ... Abstract: While an orphan disease in the USA, sickle cell disease (SCD), ... by a limited understanding of the complex pathophysiology of sickle cell disease ( SCD). ... Pauling et al's 1949 characterization of SCA as a molecular disease ..... 50% (2.5 vs 4.5 events per year) in patients assigned to HU therapy.

Ex vivo analysis of renal proximal tubular cells | BMC Cell Biology ...

bmccellbiol.biomedcentral.com/articles/10.1186/s12860-015-0058-4

Legouis et al.; licensee BioMed Central. ... GentleMACS cell dissociator (Miltenyl Biotec, California, USA) for 2 minutes at 4°C, with no added enzymes. ..... a long and aggressive step of dissociation at 37°C when massive changes can occur within .... We thank Edith Beaugey and Perrine Frère for their help in obtaining the ...

Hydroxyurea and other disease-modifying therapies in sickle cell ...

www.uptodate.com/contents/hydroxyurea-and-other-disease-modifying-therapies-in-sickle-cell-disease

Oct 29, 2015 ... ... the morbidity and mortality of highly aggressive approaches such as hematopoietic cell transplantation (HCT). ... Perrine RP, Pembrey ME, John P, et al. .... Bartolucci P, Chaar V, Picot J, et al. .... Proc Natl Acad Sci U S A 1982; 79: 4428. .... Inhibition of K transport by divalent cations in sickle erythrocytes.

Graduate School of Biomedical Sciences UTHSCSA

gsbs.uthscsa.edu/faculty/luis-penalva-ph.d

In an industrial setting (NeuroSpheres Ltd. and Layton Biosciences Inc.), ... Daadi M.M., Maag A.L. and Steinberg G.K. (2008) Adherent Self-Renewable ... 1) in tauopathy in regard to nucleocytoplasmic transport and nuclear calcium signaling ..... becoming more aggressive with time and causing AIDS (Baba et al., 1999).

Chronic sickle cell lung disease: new insights into the diagnosis ...

williams.medicine.wisc.edu/sicklelung.pdf

There are currently limited specific data on the effects of any treatment ... with SCD (Thomas et al, 1982; Powars et al, 1988; Gray et al,. 1991; Platt et al, ... Bethesda, MD 20892-1662, USA. E-mail: ..... The ventilation-perfusion (V/Q) scan is an indispensable ..... An aggressive search for associated conditions, such as iron.

TBI - Doi

dx.doi.org/10.4236/psych.2015.64033

Mar 2, 2015 ... 1Origami Brain Injury Rehabilitation Center, Mason, MI, USA ... pairments (Levin, 1995; Lezak & O'Brian, 1988; Millis et al., 2001; ..... The impact of TBI is not limited to the person who has experienced the injury, but ... tients with moderate to severe TBI are the increased aggression, ...... (Perrine, 1993)a,...

Vol 1 Ross A. McFarland Papers - Wright State University Libraries

www.libraries.wright.edu/special/collectionguides/files/fsc1vol1.pdf

W3 161 1968a v.6. 9. Abstracts of ... confirmations of "climatic aggression" in the development of ... transport aircraft / by Richard G. Snyder. ... Research / edited by E.C. Andrus et al. .... Air import potentials: China to U.S.A. / by ... Perrine, Julian A. Waller, and Lawrence S. Harris. ..... London: Tri-Med Books Limite...

PHARMACOTHERAPY IN SICKLE CELL DISEASE – STATE OF ...

europepmc.org/articles/PMC3175763

Feb 17, 2009 ... Limited information about the pharmacokinetics of .... (Constantoulakis et al, 1989 ;Perrine et al, 1988) Studies in patients with SCD .... can significantly reduce KCl co-transport activity (measured by cell K<sup>+</sup> ... and pulmonary hypertension despite aggressive medical therapy, ..... U.S.A. 1983;80:4842–4846.

A Promising Prevention Strategy for At-Risk Adolescents

tibet.emory.edu/documents/CBCT for Adolescents.pdf

Feb 21, 2012 ... Department of Religion, Emory University, Atlanta, GA, USA ... et al. 2009; Pace et al. 2010). In a randomized clinical trial .... awareness, limited access to effective emotion regulation ... validity with measures of negativity and aggression and is ..... via transportation arranged by the Department of Family.

Helpful Resources

Metformin Inhibits Growth of Human Glioblastoma Cells and ...

www.ncbi.nlm.nih.gov

Apr 13, 2015 ... GB are one of the most aggressive and deadly human cancers and despite ... of mitochondrial electron transport chain complex I (ETCI) and Liver .... For cell death, we used reagents and protocols from the FITC Annexin V/Dead Cell ..... Interestingly, Madiraju et al. recently suggested that we may need to ...

Ligand-directed signalling within the opioid receptor family

www.ncbi.nlm.nih.gov

First observed in HEK293 cells (Zheng et al., 2008), this differential ... and anti- depressant effects (Broom et al., 2002a; Saitoh et al., 2004; Perrine et al., 2006). ... sorting complex required for transport (ESCRT) machinery (Henry et al., 2011). .... However, the clinical relevance of κ agonists is limited as central activation of...

Control of MT1-MMP transport by atypical PKC during breast-cancer ...

www.ncbi.nlm.nih.gov

Apr 21, 2014 ... Control of MT1-MMP transport by atypical PKC during breast-cancer progression ... François Waharte,<sup>a,e</sup> Perrine Paul-Gilloteaux,<sup>a,e</sup> Maryse Romao,<sup>a,f</sup> Lucie Sengmanivong,a .... and highly proliferative tumors, overexpressed MT1-MMP and aPKCι vs. ..... Sakurai-Yageta M, et al. ... Proc Natl Acad Sci USA.

PDF (92 KB) - The Lancet

www.thelancet.com

transport across the nasal epithelium. Cystic fibrosis (CF), the ... USA (B J Rosenstein MD, P L Zeitlin MD) ... The importance of aggressive antimicrobial therapy is .... and CF-related liver disease is limited almost entirely to ... Patients with class IV and V mutations are often .... 2 Kerem B, Rommens JM, Buchanan JA, et al.

ACVB-AVSAB 2014 Symposium proceedings Final

www.dacvb.org

Jul 25, 2014 ... Food-related aggression in shelter dogs: A comparison of behavior .... Boston, Massachusetts, USA ... Gibbons et al.,2012) completed by 77 shelters nation- wide indicated that ..... 105.1±11.1 vs placebo, 109.6±8.5 at D-7 and 83.4±10.4 vs 83.5±8.3 at ..... for sedating cats for transportation to veterinary visits.