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en.wikipedia.org/wiki/Pioglitazone

Pioglitazone (brand name Actos) is a prescription drug of the thiazolidinedione ( TZD) class with ... It is ineffective and possibly harmful in diabetes mellitus type 1 and diabetic ketoacidosis. ... the French agency found that patients, who were taking Actos for a long time to aid in type 2 diabetes mellitus, significantly increased ...

www.ncbi.nlm.nih.gov/pubmed/17054272

Cochrane Database Syst Rev. 2006 Oct 18;(4):CD006060. Pioglitazone for type 2 diabetes mellitus. Richter B(1), Bandeira-Echtler E, Bergerhoff K, Clar C, ...

www.ncbi.nlm.nih.gov/pmc/articles/PMC3411525

Aug 3, 2010 ... Pioglitazone is a TZD which is widely used for treating patients with type 2 diabetes. Discussed in this review are the overall safety and efficacy, ...

www.ncbi.nlm.nih.gov/pmc/articles/PMC3047993

Jul 9, 2010 ... Insulin resistance and impaired beta-cell function are primary defects that occur early in the course of development of type 2 diabetes. Insulin ...

www.cochrane.org/CD006060/ENDOC_pioglitazone-for-type-2-diabetes-mellitus

Oct 18, 2006 ... Pioglitazone for type 2 diabetes mellitus. Diseases of the heart and blood vessels account for approximately 70% of all mortality in people with ...

care.diabetesjournals.org/content/36/Supplement_2/S155

Type 2 diabetes mellitus (T2DM) is a serious, chronic, and progressive disease that is ..... Efficacy and tolerability of pioglitazone in patients with type 2 diabetes ...

www.medscape.com/viewarticle/864986

Jun 17, 2016 ... But this isn't the first time pioglitazone has been shown to reduce the risk of type 2 diabetes, he stressed. In 2011, the Actos Now for Prevention ...

journals.sagepub.com/doi/abs/10.1177/14746514060060050101

The combination of metformin and pioglitazone in an early stage of type 2 diabetes enables greater likelihood that these targets can be with insulin ...

www.diabetes.co.uk/diabetes-medication/diabetes-and-actos.html

Actos is a once-daily oral medication for people with type 2 diabetes and works by increasing the body's sensitivity to its own insulin.