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Mesenchymal Stem Cell-Based Tumor-Targeted Gene ... - NCBI

www.ncbi.nlm.nih.gov/pmc/articles/PMC3424981/

Apr 24, 2012 ... The cell populations referred to as mesenchymal stem cells, or mesenchymal stromal ..... In a gastric cancer xenograft mouse model, You et al.

A novel two-step genome editing strategy with CRISPR-Cas9 ...

genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0791-1

TERT co-localizes detectably with only 5–7 % of the telomeres at a time in S- phase ... All continuously proliferating cells, like stem cells and cancer cells, require a ... locus with the CRISPR-Cas9 system, labeling the endogenous TERT protein with ...... (ATCC) and HeLa-EM2-11ht cells (Tet Systems Holdings GmbH and Co.

CD47 Is Upregulated on Circulating Hematopoietic Stem Cells and ...

www.rockefeller.edu/graduate/current/get.php?course_id=1731282279&file_id=627

Jul 23, 2009 ... lization, and that leukemic progenitors co-opt this ... By analogy with the normal HSCs, the leukemic stem cells ... whole bone marrow cells in a transplant setting (Blazar et al.,. 2001) .... V positivity between the groups (Figure S4A available online). ... systems to form anastamoses and a shared blood system.

Mesenchymal Stem Cell-Based Tumor-Targeted Gene Therapy in ...

www.kumc.edu/Documents/msctc/Bao Q, Stem Cells Dev. 2012 .pdf

4apceth GmbH & Co. ... Mary Ann Liebert, Inc. ... man umbilical cord blood- derived mesenchymal stem cells .... (2–2.5 × 108 AT-MSCs/kg in mice, 1.2 × 106 AT-MSCs in rat, ... Li et al. [76] reported that hMSCs can enhance tumor growth in vivo in an HCC s.c. model, whereas .... The Tet-on system allowed TRAIL effector and.

Autografting with CD34+ peripheral blood stem cells: retained ...

onlinelibrary.wiley.com/doi/10.1046/j.1365-2141.1999.01171.x/full

Apr 20, 2002 ... The cell suspension was frozen in 5 ml Nalgene tubes (Nalgene Co., Rochester, ... Cricket software, Philadelphia, Pa., and SAS-System for Windows<sup>®</sup>, v.612). ... In our previous study (Hohaus et al, 1997) the CD34<sup>+</sup> cells were released ... All patients received >2.5 × 10<sup>6</sup> CD34<sup>+</sup> cells/kg b.w., which was the ...

Publications - Blau Lab - Stanford University

blaulab.stanford.edu/publications.html

Blau HM, Cosgrove BD, Ho AT (2015) The central role of muscle stem cells in ..... A., Foidart, J-M., Springer, M.T., von Degenfeld, G., Dewerchin, M., Blau, H.M., et al. ... H., Sylvester, K.G., and Kay, M.A. (2008) Hepatic parenchymal replacement in ... R., Pomerantz, J.H. and Blau, H.M. (2006) A system for quantifying dynamic  .....

präventiv, personalisiert, präzise und partizipativ - 32. Deutscher ...

www.dkk2016.de/files/dkk2016/content/Download PDFs/03 Programm-Seite/01 Schwerpunkte und Downloads/Abstract_Band DKK 2016.pdf

S. Karger Verlag für Medizin und Naturwissenschaften GmbH. Wilhelmstr. .... the tetracycline-controlled transcription activation system (“Tet-off sys- tem”) and RNA ... stem cells and human Her2-positive breast cancer cells into neonatal NSG mice. .... kg q3w) vs. B: T-DM1 ..... about 3 was calculated (Cybulski et al. 2011).

genesdev232710 1..15 - Genes & Development - Cshlp.org

genesdev.cshlp.org/content/early/2013/11/26/gad.232710.113.full.pdf

Nov 7, 2013 ... GmbH and Company KG, 1120 Vienna, Austria; 8Laboratory of Biochemistry and Molecular .... model of MLL-AF9/NrasG12D AML (Zuber et al.

Dual‐regulated expression of C/EBP‐α and BMP‐2 enables ...

nar.oxfordjournals.org/content/32/1/e1.full

Mesenchymal stem cells are multipotent cells which can differentiate into ... Combination of PIP and TET systems enabled four different digital ... from pCF50 (pAI‐C/EBPα←PhCMV*‐1‐stuffer‐PPIR8→E7‐HA‐pAII; C.Fux et al., .... Co., St Louis, MO). ... G418 was obtained form Calbiochem‐Novabiochem Inc. (La Jolla, CA), ...

Btk expression is controlled by Oct and BOB.1/OBF.1

nar.oxfordjournals.org/content/34/6/1807.full.pdf

Mar 31, 2006 ... embryonic stem cells (49), Btk expression was either reduced or not affected ... electroporation (Bio-Rad) with 450 V and 250 mF in phosphate ... (A. Rolink, Basel) and 5% Primatone (PAN Systems GmbH). ..... The fold induction upon co- transfection of Oct2, BOB.1/OBF.1 or PU.1 or ..... Copeland,N.G. et al.

More Info

CD47 is up-regulated on circulating hematopoietic stem cells and ...

www.ncbi.nlm.nih.gov

Jul 23, 2009 ... By analogy with the normal HSCs, the leukemic stem cells (LSCs) must also be able ... (Miyashita et al., 2004), and T-cell co-stimulation (Reinhold et al., 1997). .... systems to form anastamoses and a shared blood system (Wright et al., 2001b ). .... Only cells transduced with Tet-CD47 were able to give rise to ...

Mesenchymal Stem Cell-Based Tumor-Targeted Gene Therapy in ...

online.liebertpub.com

Jun 26, 2012 ... <sup>4</sup>apceth GmbH & Co. ... T he cell populations referred to as mesenchymal stem cells, ..... Importantly, even at the highest cell dose examined (2–2.5×10<sup>8</sup> AT- MSCs/kg in ... Li et al. [76] reported that hMSCs can enhance tumor growth in vivo ... The Tet-on system allowed TRAIL effector and GFP reporter gene ...

Cell Death and Disease - Transcriptional and metabolic adaptation ...

www.nature.com

May 8, 2014 ... A K Krug, S Gutbier, L Zhao, D Pöltl, C Kullmann, V Ivanova, ... Luxembourg; <sup>7</sup> Boehringer Ingelheim Pharma GmbH & Co. KG Div. ... ATF-4; reactive oxygen species; respiratory chain; metabolomics; systems toxicology; transcriptomics ...... von Stechow L, Siddappa R, Pines A, Bahjat M, Haazen LC et al.