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TET Systems GmbH & Co. KG


Company. TET Systems is located in Heidelberg, Germany. » Read more ... News. BizCom Japan, Inc. and TET Systems GmbH & Co. KG sign... » Read more  ...

Contact - TET Systems


TET Systems is located in the Technology Park on the campus of the University of Heidelberg. You can reach us at: TET Systems GmbH & Co. KG

RUNX1B Expression Is Highly Heterogeneous and Distinguishes ...


Jan 25, 2016 ... Of these, P2-hCD4 was co-expressed in 12% of Gr1<sup>high</sup> granulocytes, ..... would impact the overall homeostasis of the adult blood system. .... Ben-Ami et al. previously demonstrated RUNX1 enhances the ... 545mg/kg Doxycycline (ssniff Spezialdiäten GmbH) for 8 days prior to ..... Stem Cells 22: 158–168.

CD47 is up-regulated on circulating hematopoietic stem cells and ...


Jul 23, 2009 ... By analogy with the normal HSCs, the leukemic stem cells (LSCs) must also ... extension (Miyashita et al., 2004), and T-cell co-stimulation (Reinhold et al., 1997 ). .... In agreement with previous results (Blazar et al., 2001), we found that ..... Only cells transduced with Tet-CD47 were able to give rise to tumors ...

Antagonistic control of a dual-input mammalian gene switch by food ...


Jul 16, 2014 ... Most of these mammalian transgene-control systems are compatible with each ... (NOAEL) of dietary sodium benzoate was estimated to be 1400 mg/kg (33). ... telomerase-immortalized human mesenchymal stem cells (hMSCs (39)) ... L0022 –100) at 37°C in a humidified atmosphere containing 5% CO2.

Full Text HTML - Mary Ann Liebert, Inc. publishers


Jun 26, 2012 ... T he cell populations referred to as mesenchymal stem cells, or mesenchymal stromal ..... In a gastric cancer xenograft mouse model, You et al.

A novel two-step genome editing strategy with CRISPR-Cas9 ...


TERT co-localizes detectably with only 5–7 % of the telomeres at a time in S- phase ... All continuously proliferating cells, like stem cells and cancer cells, require a ... locus with the CRISPR-Cas9 system, labeling the endogenous TERT protein with ...... (ATCC) and HeLa-EM2-11ht cells (Tet Systems Holdings GmbH and Co.

The impact of human EGFR kinase domain mutations on lung ...


A similar finding has been observed in NSCLC cell lines ( Gazdar et al., 2004, Sordella et al., ... Generation of Tet-op-hEGFR L858R-Luc and Tet-op-hEGFR Del-Luc alleles .... does not play a crucial role in lung tumorigenesis in our system ( Seftor et al., 1998). ..... For targeted therapies, either erlotinib (Biaffin GmbH & Co.

Supplemental Information Inhibition of De Novo NAD ... - Cell


and H&E stained sections from hURI-tetOFFhep mice at 10 weeks of age. Dotted black ... (V) Schematic representation of the doxycycline treatment used in hURI- tetOFFhep mice as to take advantage of the switch-ability system. Mice were ..... Mice were fed 2.24 mg/kg of body weight per day (Menon et al., 2012). Ultrasound ...

Publications - Blau Lab - Stanford University


Blau HM, Cosgrove BD, Ho AT (2015) The central role of muscle stem cells in ..... A., Foidart, J-M., Springer, M.T., von Degenfeld, G., Dewerchin, M., Blau, H.M., et al. ... H., Sylvester, K.G., and Kay, M.A. (2008) Hepatic parenchymal replacement in ... R., Pomerantz, J.H. and Blau, H.M. (2006) A system for quantifying dynamic  .....

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Company - TET Systems


TET Systems is located in Heidelberg, Germany. The company was founded by the inventors of the Tet Technology and holds the Tet Technology IP portfolio ...

Mesenchymal Stem Cell-Based Tumor-Targeted Gene Therapy in ...


Apr 24, 2012 ... The cell populations referred to as mesenchymal stem cells, or mesenchymal stromal ..... In a gastric cancer xenograft mouse model, You et al.

Abnormal tau induces cognitive impairment through two different ...


Feb 18, 2016 ... The expression of the PH-Tau is controlled by the Tet-Off system which can .... < 0.001), and further increased in PH-Tauhigh mice 11.3% ± 1.2% (P < 0.01 vs. .... DeCalignon et al., using live-imaging, proposed that caspase activation ... addition of doxycycline (1 g/kg in the food, BioServ Inc) (Tet-Off system).