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Sorafenib Hepatobiliary Disposition: Mechanisms of Hepatic ... - NCBI

www.ncbi.nlm.nih.gov/pmc/articles/PMC3657095/

... tosylate, and decynium 22 were provided by Bayer HealthCare AG (Wuppertal, Germany). ... The Km and Vmax values were obtained by fitting the Michaelis- Menten ..... Sorafenib, a P-gp and Bcrp substrate (Hu et al., 2009; Gnoth et al., 2010; .... American Association of Pharmaceutical Scientists Annual Meeting; 2010 ...

US Supreme Court Orders - FindLaw - US Supreme Court Center

supreme.findlaw.com/supreme_court/orders/1999/100499.html

SCH., ET AL. 98-1768 BUCKMAN COMPANY V. PLAINTIFF'S LEGAL COMMITTEE 98-1836 U. S. HEALTHCARE SYSTEMS, PA V. PA HOSP. INS. CO. , ET AL.

Full Text - Drug Metabolism and Disposition - American Society for ...

dmd.aspetjournals.org/content/41/6/1179.full

... saturable with a Michaelis-Menten constant of 3.80 ± 2.53 µM and a Vmax of 116 ± 42 pmol/mg/min. ... of sorafenib occur within 2 to 3 hours after a single oral dose (Strumberg et al., ... decynium 22 were provided by Bayer HealthCare AG ( Wuppertal, Germany). ...... Ming X,; Ju W,; Wu H,; Tidwell RR,; Hall JE,; Thakker DR.

Role of the Plasma Membrane Transporter of Organic Cations OCT1 ...

www.hindawi.com/journals/bmri/2013/692071/

Jul 4, 2013 ... (v) Role of Interactions among OCT1 Substrates in Liver Pharmacology. ... J. Bruix, J. L. Raoul, M. Sherman et al., “Efficacy and safety of sorafenib in .... O. Briz , M. J. Monte, A. G. Blazquez, and R. I. R. Macias, “Genetic variants in .... as a fluorescent probe substrate,” Journal of Pharmaceutical Sciences, vol.

Nutrients | Free Full-Text | Effects of Dietary Fat and Saturated Fat ...

www.mdpi.com/2072-6643/6/11/4678/htm

Oct 28, 2014 ... <sup>1</sup> p < 0.017 compared to CONT LFD.<sup>2</sup> p < 0.017 compared to CONT HFD.<sup>3</sup> p < 0.017 HFD vs. ... version 2.5.3.0 (Philips Healthcare, Andover, MA, USA) whole body scanner ... (GC/MS) using the procedure detailed by D. Milatovic et al. ..... Utzschneider, K.M.; Bayer-Carter, J.L.; Arbuckle, M.D.; Tidwell, J.M.; .....

Drug discovery and development for neglected parasitic diseases ...

www.nature.com/nchembio/journal/v2/n12/full/nchembio837.html

These compounds continue to be examined in preclinical studies (R. Tidwell, UNC, ... In more recent work, Gilbert et al. identified trimethoprim analogs that are .... 1 and phase 2 studies under the auspices of MMV and industrial partner Bayer . .... Few in the pharmaceutical industry viewed kinases as viable targets until the  ...

The effects of different thermal treatments and organic acid levels in ...

ps.oxfordjournals.org/content/93/6/1440.full

Gut microbiota plays an important role for animal health, performance, and product safety (Torok et al., 2011). Interest in finding an effective and economically ...

In vitro efficacy of di-cationic compounds - Antimicrobial Agents and ...

aac.asm.org/content/early/2011/07/18/AAC.00478-11.full.pdf

Jul 18, 2011 ... supplied by from Mepha Pharma AG (Aesch, BL, Switzerland), and mefloquine. 101 ... levoflaxin (Aventis, Meyrin, Switzerland), 20 µg/ml ciprofloxacin (Bayer, Zürich,. 109 ... Treatments were carried out as described in Stadelmann et al. (47) . ..... Gelmedin, V., R. Caballero-Gamiz, and K. Brehm. 2008.

United States Department of Justice - PlainSite

www.plainsite.org/profiles/united-states-department-of-justice/page-1/table-firmdockets

United States Department of Justice's PlainSite profile, including litigation, intellectual property, public records and more.

Nonalcoholic Fatty Liver Disease - Today's Dietitian

www.todaysdietitian.com/newarchives/010614p48.shtml

The effects of aerobic training vs. resistance training also have been debated. Several studies .... Browning JD, Szczepaniak LS, Dobbins R, et al. Prevalence of  ...

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Dietary habits and behaviors associated with nonalcoholic fatty liver ...

www.ncbi.nlm.nih.gov

Feb 21, 2014 ... Alisi A, Manco M, Panera N, Nobili V. Association between type two diabetes .... Centis E, Moscatiello S, Bugianesi E, Bellentani S, Fracanzani AL, .... Wada K, Zhang HM, Matsushita K, Sugiura K, Takefuji S, et al. ... Christen AG, Christen JA. .... Utzschneider KM, Bayer-Carter JL, Arbuckle MD, Tidwell JM, ...

Citizens for Consume, et al v. Abbott Laboratories,, et al - Law360

www.law360.com

... for Consume, et al v. Abbott Laboratories,, et al, case number 1:01-cv-12257, from Massachusetts Court. ... AG Scientific, Inc. ... Nicholas H. Patton, Patton Tidwell Sandefur. Jeffrey I. ..... 04/14/2010. Bayer Pharmaceuticals Corporation ...

Entinostat - AdisInsight

adisinsight.springer.com

Jun 1, 2016 ... In June 2006, Schering AG was acquired by Bayer, and was renamed as Bayer Schering Pharma AG . Bayer Schering Pharma was renamed as Bayer HealthCare ..... patients, median survival duration was more favourable with the combination (9.4 vs ..... Gojo I, Gore SD, Jiemjit A, Greer J, Tidwell ML, et al.