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Role of the Plasma Membrane Transporter of Organic Cations OCT1 ...


Jul 4, 2013 ... J. Bruix, J. L. Raoul, M. Sherman et al., “Efficacy and safety of sorafenib in ... roles , and biopharmaceutical implications,” Pharmaceutical Research, vol. ... V. Gorboulev, H. Koepsell, and M. Schmid, “The two human organic cation ... O. Briz , M. J. Monte, A. G. Blazquez, and R. I. R. Macias, “Genetic variants in ...

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CLAUDIO ABAECHERLI, Lonza AG, Visp, Switzerland ..... pharmaceutical activity found for some b-lac- ..... 10 T. T. Tidwell: ''Ketene Chemistry, the Second Golden ... Bissing, V. Gash). ... 53 BASF, US 5 359 122, 1994 (M. Huellmann et al. ) ... Bayer, DE. 832 440, 1949. 79 Lonza AG, GB 852 865, 1960 (W. Moser, R. Perren ).

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Jun 22, 2010 ... and other kinases, sorafenib (Nexavar™, Bayer and Onyx pharmaceuticals) and sunitinib (Sutent™, Pfizer), have been approved based on ... In a phase II clinical trial by Karp et al. bevacizumab was administered after ..... Loges S, Heil G, Bruweleit M, Schoder V, Butzal M, Fischer U, Gehling UM,. Schuch G ...

Drug discovery and development for neglected parasitic diseases ...


These compounds continue to be examined in preclinical studies (R. Tidwell, UNC, ... In more recent work, Gilbert et al. identified trimethoprim analogs that are .... 1 and phase 2 studies under the auspices of MMV and industrial partner Bayer . .... Few in the pharmaceutical industry viewed kinases as viable targets until the  ...

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Nov 10, 2014 ... Using a multi-tracer approach Donnelly et al. ... 2 diabetes (T2D) had significantly more liver TG than age- and BMI-matched controls (121 vs.

Phosphodiesterase inhibitors as a new generation of antiprotozoan ...


inhibitor roflumilast (Daxas®; Nycomed Pharma; for chronic obstructive ... or vardenafil (Levitra®; Bayer) for erectile dysfunction. ... these catalytic domains, TbrPDEB1 of T. brucei [KE ET AL., UNPUBLISHED ..... Petry F, Jakobi V, Tessema TS. .... Boykin DW, Ismail MA, Hall JE, Tidwell RR, Brun R. New treatment option for.

United States Department of Justice - PlainSite


United States Department of Justice's PlainSite profile, including litigation, intellectual property, public records and more.

Aus dem Departement für Nutztiere (Direktor: Prof - Universität Zürich


WINTERS et al., 2006; TIDWELL et al., 2007; JUNG et al., 2010; SEILER et al.,. 2010; DENNLER .... kranial und wird von der V. cava cranialis zunächst rechts und dann dorsal zum. Brusteingang ..... Test®, Roche Pharma AG, Grenzach, Deutschland) ... Dazu wurde ein Kontrastmittel (Ultravist®-370, Bayer Schering. Pharma ...

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Oct 28, 2014 ... <sup>1</sup> p < 0.017 compared to CONT LFD.<sup>2</sup> p < 0.017 compared to CONT HFD.<sup>3</sup> p < 0.017 HFD vs. ... (GC/MS) using the procedure detailed by D. Milatovic et al. ..... Utzschneider, K.M.; Bayer-Carter, J.L.; Arbuckle, M.D.; Tidwell, J.M.; Richards, .... 1996-2015 MDPI AG (Basel, Switzerland) unless otherwise stated.

Building a needs-driven pharmaceutical R&D agenda for neglected ...


Chapter 6.9: A Needs-Based Pharmaceutical R&D Agenda for Neglected Diseases .... Develop a global needs-driven essential health R&D agenda, and; Create appropriate .... in the context of neglected diseases carried out by De poortere et al. ..... v AIDS antiviral drugs (20 approved antiretrovirals and antiproteases) and ...

Helpful Resources

Sorafenib Hepatobiliary Disposition: Mechanisms of Hepatic Uptake ...


... tosylate, and decynium 22 were provided by Bayer HealthCare AG (Wuppertal, Germany). ... The Km and Vmax values were obtained by fitting the Michaelis- Menten ..... This finding contradicts work by Hu et al., who reported no appreciable .... American Association of Pharmaceutical Scientists Annual Meeting; 2010 Nov ...

View List of Cases - Class Action Lawyers, Attorneys, Complex ...


Joint School District No.2 et al View Case »; Aalen et al v. ... v. Novartis Pharmaceuticals Corp. ..... Boehringer Ingelheim Pharmaceuticals I View Case »; Allen v. ...... SUPERIOR AG RESOURCES COOPERATIVE, I View Case »; Bakeer v.

1 CURRICULUM VITAE Priv. Doz. Dr. Dr. Christian Michael Grimm


University, Boston, MA, USA; Freie Universität Berlin, Germany; Bayer AG, Bayer Health Care,. Leverkusen ... Pharmaceutical R&D, Leverkusen, Germany (Dr. Peter Kurka, PhD). 10/1995 ..... TRPML3(I362T/A419P)-expressing cells were annexin V- positive .... of capsaicin voltage was normal (at 201C; Grandl et al, 2010).

False Claims Cases Filed January 1, 2007 – June 30, 2013 - Navigant


Jun 28, 2013 ... United States Of America V. The Roby Institute Et Al. United States of ... Crawley V. Harrisburg Area Community College Et Al. Todd A. Crawley.



... Bailey Galyen et. al., Kenneth T. Fibich, Fletcher Vines Trammell, W. Michael Leebron, ... OH, Justin Kurt Truelove, Patton Tidwell, Texarkana, TX, Jeffrey D. Schreiber, .... See Part V, infra; see also In re Zyprexa Prods. ..... Oct. 03, 2005) ( MDL litigation against pharmaceutical company Bayer Co. .... see, e.g., Ruhrgas AG v.