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Titin - Wikipedia

en.wikipedia.org/wiki/Titin

Titin /ˈtaɪtɪn/, also known as connectin, is a protein that, in humans, is encoded by the TTN .... The titin protein is located between the myosin thick filament and the Z disk. Titin...

The role of titin in eccentric muscle contraction | Journal of ...

jeb.biologists.org/content/217/16/2825

Here, I suggest, and provide evidence, that a third filament, titin, is involved in force regulation of sarcomeres by adjusting its stiffness in an activation- dependent ...

Titin-thin filament interaction and potential role in muscle function.

www.ncbi.nlm.nih.gov/pubmed/10987081

Titin-thin filament interaction and potential role in muscle function. ... Titin ( connectin) is a giant polypeptide that forms a single-molecule filamental structure  ...

Titin Structure & Function - Proteopedia, life in 3D

www.proteopedia.org/wiki/index.php/Titin_Structure_&_Function

Jul 11, 2012 ... Titin is a multi-domain structure that which is found to be composed of two ... The protein molecules plays a role in thick-filament and sacromere ...

Titin - Faculty of Biological Sciences - University of Leeds

www.fbs.leeds.ac.uk/research/contractility/titin.htm

These have two main functions: In the thick (myosin) filament part of the myofibril we have proposed the titin molecule regulates exact myosin assembly by acting ...

The Giant Protein Titin | Circulation Research

circres.ahajournals.org/content/80/2/290

The determination of the cDNA sequence of human cardiac titin has shown that the cardiac titin filament is formed by a single, giant, 27 000-residue-long ...

Is titin a 'winding filament'? A new twist on muscle contraction ...

rspb.royalsocietypublishing.org/content/279/1730/981

Sep 7, 2011 ... We propose a 'winding filament' mechanism for titin's role in active muscle. First, we hypothesize that Ca<sup>2+</sup>-dependent binding of titin's N2A ...

www.ask.com/youtube?q=Titin Filament&v=lQK9hbBLzbM
Jul 22, 2014 ... Titin /ˈtaɪtɪn/, also known as connectin, is a protein that, in humans, is encoded by the TTN gene. Titin is a giant protein that functions as a ...

Roles of Titin in the Structure and Elasticity of the Sarcomere

www.hindawi.com/journals/bmri/2010/612482/

May 13, 2010 ... The size and structure of the thick filament part of titin is conserved, which is consistent with the conserved structure of thick filaments in ...

Titin: properties and family relationships : Article : Nature Reviews ...

www.nature.com/nrm/journal/v4/n9/full/nrm1198.html

The titin molecule is a flexible filament that is more than 1 mu m long. This spans half the sarcomere, the repeating contractile unit that gives striated muscle its ...