Web Results

Titin

en.wikipedia.org/wiki/Titin

Titin /ˈtaɪtɪn/, also known as connectin, is a protein that, in humans, is encoded by the TTN ... The titin protein is located between the myosin thick filament and the Z disk. Titin ...

Titin-thin filament interaction and potential role in muscle function.

www.ncbi.nlm.nih.gov/pubmed/10987081

Adv Exp Med Biol. 2000;481:319-33; discussion 334-5. Titin-thin filament interaction and potential role in muscle function. Jin JP(1). Author information:

Titin Structure & Function - Proteopedia, life in 3D

www.proteopedia.org/wiki/index.php/Titin_Structure_&_Function

Jul 11, 2012 ... Titin is a multi-domain structure that which is found to be composed of two ... The protein molecules plays a role in thick-filament and sacromere ...

Roles of Titin in the Structure and Elasticity of the Sarcomere

www.hindawi.com/journals/bmri/2010/612482/

May 13, 2010 ... The size and structure of the thick filament part of titin is conserved, which is consistent with the conserved structure of thick filaments in ...

The Giant Protein Titin: A Regulatory Node That Integrates Myocyte ...

www.jbc.org/content/286/12/9905.full

Mar 25, 2011 ... The titin filament inserts, with its NH2 terminus, in the Z-disk and reaches all the way to the center of the sarcomere, the M-band (Fig. 1).

The Giant Protein Titin | Circulation Research

circres.ahajournals.org/content/80/2/290

The determination of the cDNA sequence of human cardiac titin has shown that the cardiac titin filament is formed by a single, giant, 27 000-residue-long ...

www.ask.com/youtube?q=Titin Filament&v=lQK9hbBLzbM
Jul 22, 2014 ... Titin /ˈtaɪtɪn/, also known as connectin, is a protein that, in humans, is encoded by the TTN gene. Titin is a giant protein that functions as a ...

Frontiers | Titin isoform size is not correlated with thin filament length ...

journal.frontiersin.org/article/10.3389/fphys.2014.00035/full

The mechanisms controlling thin filament length in muscle remain controversial. It was recently reported that thin filament length was related to titin size, and that ...

Mutations of TTN, encoding the giant muscle filament titin, cause ...

www.nature.com/ng/journal/v30/n2/full/ng815.html

Jan 14, 2002 ... We show that mutations in the gene encoding giant-muscle filament titin (TTN) cause autosomal dominant DCM linked to chromosome 2q31 ...

titin and nebulin content in human skeletal muscle following

www.utoledo.edu/med/depts/medicine/endocrinology/pdfs/Titin_and_nebulin_content_in_h.pdf

Titin and nebulin content were significantly (P < 0.05) reduced after exercise by 30 and 15%, ... lin, along with actin, forms the thin filament.13,17 In addition to ...

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The role of titin in eccentric muscle contraction | Journal of ...

jeb.biologists.org

Here, I suggest, and provide evidence, that a third filament, titin, is involved in force regulation of sarcomeres by adjusting its stiffness in an activation- dependent ...

Is titin a 'winding filament'? A new twist on muscle contraction ...

rspb.royalsocietypublishing.org

Aug 27, 2011 ... We propose a 'winding filament' mechanism for titin's role in active muscle. First, we hypothesize that Ca<sup>2+</sup>-dependent binding of titin's N2A ...

Titin - Faculty of Biological Sciences - University of Leeds

www.fbs.leeds.ac.uk

These have two main functions: In the thick (myosin) filament part of the myofibril we have proposed the titin molecule regulates exact myosin assembly by acting ...