Titin /ˈtaɪtɪn/, also known as connectin, is a protein that, in humans, is encoded
by the TTN ... The titin protein is located between the myosin thick filament and
the Z disk. Titin ...
Adv Exp Med Biol. 2000;481:319-33; discussion 334-5. Titin-thin filament
interaction and potential role in muscle function. Jin JP(1). Author information:
Jul 11, 2012 ... Titin is a multi-domain structure that which is found to be composed of two ... The
protein molecules plays a role in thick-filament and sacromere ...
May 13, 2010 ... The size and structure of the thick filament part of titin is conserved, which is
consistent with the conserved structure of thick filaments in ...
Mar 25, 2011 ... The titin filament inserts, with its NH2 terminus, in the Z-disk and reaches all the
way to the center of the sarcomere, the M-band (Fig. 1).
The determination of the cDNA sequence of human cardiac titin has shown that
the cardiac titin filament is formed by a single, giant, 27 000-residue-long ...
Jul 22, 2014 ... Titin /ˈtaɪtɪn/, also known as connectin, is a protein that, in humans, is encoded
by the TTN gene. Titin is a giant protein that functions as a ...
The mechanisms controlling thin filament length in muscle remain controversial. It
was recently reported that thin filament length was related to titin size, and that ...
Jan 14, 2002 ... We show that mutations in the gene encoding giant-muscle filament titin (TTN)
cause autosomal dominant DCM linked to chromosome 2q31 ...
Titin and nebulin content were significantly (P < 0.05) reduced after exercise by
30 and 15%, ... lin, along with actin, forms the thin filament.13,17 In addition to ...