Amifostine (Ethiofos) is a cytoprotective adjuvant used in cancer chemotherapy
and radiotherapy involving DNA-binding chemotherapeutic agents. It is marketed
(am-i-FOS-teen). Trade Names:Ethyol®. Amifostine is the generic name for the
trade name drug Ethyol. In some cases, health care professionals may use the ...
Easy to read patient leaflet for amifostine. Includes indications, proper use,
special instructions, precautions, and possible side effects.
Notably, the landmark study by Brizel et al of patients who were administered
postoperative RT demonstrated reduced xerostomia in the amifostine arm.
Medscape - Indication-specific dosing for Ethyol, (amifostine), frequency-based
adverse effects, comprehensive interactions, contraindications, pregnancy ...
ETHYOL (amifostine) is an organic thiophosphate cytoprotective agent known
chemically as 2-[(3-aminopropyl)amino]ethanethiol dihydrogen phosphate (ester)
The aminothiol amifostine (Ethyol) is the subject of extensive research as a
protector. Several studies have demonstrated that amifostine protects normal
Oncologist. 2007 Jun;12(6):738-47. Amifostine: the first selective-target and
broad-spectrum radioprotector. Kouvaris JR(1), Kouloulias VE, Vlahos LJ.
Amifostine Base is a phosphorylated aminosulfhydryl compound with
cytoprotective activity. Amifostine is dephosphorylated by alkaline phosphatase
to an ...
The pharmacokinetics of cisplatin was investigated in 13 patients receiving 18
courses of cisplatin alone or in combination with amifostine to investigate the ...