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Drotrecogin alfa

en.wikipedia.org/wiki/Drotrecogin_alfa

Drotrecogin alfa (activated) is a recombinant form of human activated protein C that has anti-thrombotic, anti-inflammatory, and profibrinolytic properties.

Drotrecogin alfa: Indications, Side Effects, Warnings - Drugs.com

www.drugs.com/cdi/drotrecogin-alfa.html

Easy to read patient leaflet for drotrecogin alfa. Includes indications, proper use, special instructions, precautions, and possible side effects.

Drotrecogin Alfa (Activated) in Adults with Septic Shock — NEJM

www.nejm.org/doi/full/10.1056/NEJMoa1202290

May 22, 2012 ... There have been conflicting reports on the efficacy of recombinant human activated protein C, or drotrecogin alfa (activated) (DrotAA), for the ...

Xigris (Drotrecogin alfa) Drug Information: Side Effects and Drug ...

www.rxlist.com/xigris-drug/side-effects-interactions.htm

Learn about drug side effects and interactions for the drug Xigris (Drotrecogin alfa).

Drotrecogin alfa (activated) for severe sepsis | Guidance and ... - NICE

www.nice.org.uk/guidance/ta84

Sep 22, 2004 ... On 25 October 2011, Eli Lilly and Company announced the withdrawal of its Xigris (drotrecogin alfa [activated]) product in all markets following ...

Xigris (drotrecogin alfa) Drug Side Effects, Interactions, and ...

www.emedicinehealth.com/drug-drotrecogin_alfa/article_em.htm

Drug information on Xigris (drotrecogin alfa), includes drug pictures, side effects, drug interactions, directions for use, symptoms of overdose, and what to avoid.

Voluntary market withdrawal of Xigris [drotrecogin alfa ... - FDA

www.fda.gov/Drugs/DrugSafety/ucm277114.htm

Oct 25, 2011 ... FDA Drug Safety Communication: Voluntary market withdrawal of Xigris [ drotrecogin alfa (activated)] due to failure to show a survival benefit.

DrugBank: Drotrecogin alfa

www.drugbank.ca/drugs/DB00055

Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. It is a glycoprotein of approximately 55 kilodalton molecular ...

Pharmacotherapy Update | Drotrecogin alfa-Recombinant Human ...

www.clevelandclinicmeded.com/medicalpubs/pharmacy/janfeb2002/drotrecogin.htm

Drotrecogin alfa [recombinant Human Activated Protein C (Xigris™)], was recently approved by the FDA for the reduction of mortality in adult patients with severe ...

Drotrecogin alfa (activated) in severe sepsis - The Lancet Infectious ...

www.thelancet.com/journals/laninf/article/PIIS1473-3099(12)70269-4/fulltext?rss=yes

Demographic characteristics and average acute physiology and chronic health evaluation (APACHE II) scores were much the same in the randomised clinical ...

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Drotrecogin alfa (activated): the first FDA-approved treatment for ...

www.ncbi.nlm.nih.gov

Drotrecogin alfa (activated) (Xigris, Eli Lilly and Company, Indianapolis, Ind) is a recombinant form of human activated protein C. It was approved by the Food ...

Sepsis Drug Xigris Pulled From Worldwide Market - Medscape

www.medscape.com

Oct 25, 2011 ... October 25, 2011 — Eli Lilly is withdrawing activated drotrecogin alfa (Xigris), a drug intended to treat severe sepsis in high-risk patients, from ...

Xigris (Drotrecogin alfa) Drug Information: Description, User ...

www.rxlist.com

Sep 1, 2009 ... Xigris (drotrecogin alfa (activated)) is a recombinant form of human activated protein C. An established human cell line possessing the ...