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Levobupivacaine (rINN) /liːvoʊbjuːˈpɪvəkeɪn/ is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine.


Levobupivacaine is extensively metabolized with no unchanged levobupivacaine detected in urine or feces. In vitro studies using [14 C] levobupivacaine ...


In recent years levobupivacaine, the pure S (−)-enantiomer of bupivacaine, emerged as a safer alternative for regional anesthesia than its racemic parent.


The majority of in vitro, in vivo and human pharmacodynamic studies of nerve block indicate that levobupivacaine has similar potency to bupivacaine. However  ...


Best Pract Res Clin Anaesthesiol. 2005 Jun;19(2):247-68. Bupivacaine, levobupivacaine and ropivacaine: are they clinically different? Casati A(1), Putzu M.


The quest for searching newer and safer anesthetic agents has always been one of the primary needs in anesthesiology practice. Levobupivacaine, the pure S ...


Sep 1, 2014 ... Mann and colleagues used 7.5–10 mg of bupivacaine 0.25%, and the identical volumes of levobupivacaine. In the bupivacaine group, ...


Aug 7, 2015 ... Levobupivacaine should be administered only by, or under the supervision of, a clinician having the necessary training and experience.


Mar 4, 2014 ... To compare two intrathecal anaesthetics, bupivacaine and levobupivacaine, for their effects on motor and sensory blockade and ...


Nov 15, 2012 ... Levobupivacaine is an enantiomer of racemic bupivacaine with less cardiotoxicity and neurotoxicity. The study was conducted from April 2010 ...