Lofexidine is an α2A adrenergic receptor agonist, historically used as an
antihypertensive, but more commonly used to alleviate the physical symptoms of
Lofexidine tablets are used to replace opiates when the usage of opiods is trying
to be reduced.
J Subst Abuse Treat. 2001 Jul;21(1):11-7. Lofexidine versus clonidine in rapid
opiate detoxification. Gerra G(1), Zaimovic A, Giusti F, Di Gennaro C, Zambelli U,
Lofexidine (Subutex, Buprenorphine, Britoflex, Naltraxone). Lofexidine
SCIENTIFIC TERM: 17-(cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-
Lofexidine (Britlofex) for opioid withdrawal. Thu Apr 26, 2012 5:14 am. I came
across this drug today. Apparently it is based on Clonidine, but has had far better
Oct 8, 2015 ... The dosage of lofexidine should be titrated according to the patient's response.
Initial dosage should be 0.8mg per day in divided doses.
Lofexidine reduces the effect of noradrenaline, thus reducing opiate withdrawal
symptoms. However, it does not repress all opiate withdrawal symptoms, ...
Apr 12, 2012 ... Lofexidine (Britlofex) is an alpha2-adrenergic receptor agonist commonly used to
alleviate some of the physical symptoms of opiate withdrawal ...
Jun 21, 2009 ... BritLofex is the brand name for lofexidine hydrochloride. It belongs to a group of
medicines called alpha2 adrenergic agonists. BritLofex comes ...
Identifier: NHSG/Guid/lof/MGPG786. - i -. Guidance For The Use Of Lofexidine In
The Symptomatic Management Of Opioid Withdrawal By Clinicians – Version 5.