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Lofexidine (sold under the brand names: Britlofex and Kai Er Ding) is an α2A- adrenergic receptor agonist, historically used as an anti-hypertensive, but more ...

Lofexidine versus clonidine in rapid opiate detoxification.


J Subst Abuse Treat. 2001 Jul;21(1):11-7. Lofexidine versus clonidine in rapid opiate detoxification. Gerra G(1), Zaimovic A, Giusti F, Di Gennaro C, Zambelli U,  ...

Lofexidine for opiate detoxification: review of recent randomised and ...


The objective of this article was to review the data from recently published trials of lofexidine in the treatment of opiate withdrawal, with particular attention to ...

Clonidine, lofexidine and similar medications for the management of ...


Mar 31, 2014 ... Review question. We reviewed the evidence about the effect of alpha2- adrenergic agonists (clonidine, lofexidine, guanfacine and tizanidine) in ...

Lofexidine tablets | Patient


Lofexidine tablets are used to replace opiates when the usage of opiods is trying to be reduced.

Lofexidine (Subutex, Buprenorphine, Britoflex, Naltraxone) | Ascert


Lofexidine (Subutex, Buprenorphine, Britoflex, Naltraxone). Lofexidine SCIENTIFIC TERM: 17-(cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy- 18 ...

Lofexidine « DrugScope


Lofexidine is prescribed to reduce the symptoms of withdrawal from opiate addiction during supervised detoxification. The drug acts on alpha-adrenoceptors in ...

DrugBank: Lofexidine


Oct 21, 2007 ... Lofexidine is an alpha2-adrenergic receptor agonist. It can be used as a short acting anti-hypertensive, but is mostly used to help relieve ...

Lofexidine - Drugs Forum


Apr 12, 2012 ... Lofexidine (Britlofex) is an alpha2-adrenergic receptor agonist commonly used to alleviate some of the physical symptoms of opiate withdrawal ...

BritLofex Tablets 0.2mg - Summary of Product Characteristics (SPC ...


Oct 8, 2015 ... The dosage of lofexidine should be titrated according to the patient's response. Initial dosage should be 0.8mg per day in divided doses.

Popular Q&A
Q: What is lofexidine?
A: Lofexidine is an alpha2-adrenergic receptor agonist, most commonly used to alleviate physical symptoms of heroin and opiate withdrawal. Read More »
Source: www.kgbanswers.co.uk
Q: How to take lofexidine
A: Lofexidine may be used as part of a detoxification programme in hospital or at home. Each programme is tailored to meet a person's individual needs - no two det... Read More »
Source: www.patient.co.uk
Q: How should lofexidine be prescribed for detoxification?
A: Lofexidine needs to be monitored carefully. The blood pressure and pulse rate should be measured daily while the dose is increasing, so it may not be ideal for ... Read More »
Source: www.cks.nhs.uk
Q: How should lofexidine be prescribed for detoxification?
A: Lofexidine therapy is most likely to be successful in people who: Have shorter drug and treatment histories. Have made an informed and clinically appropriate de... Read More »
Source: www.cks.nhs.uk
Helpful Resources

US WorldMeds - Lofexidine Hydrochloride for treatment of opiate ...


Lofexidine is approved in the United Kingdom as BritLofex<sup>®</sup> and has been used in successful detoxification of more than 200,000 opiate addicts. US WorldMeds ...