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Lofexidine (sold under the brand names: Britlofex and Kai Er Ding) is an α2A- adrenergic receptor agonist, historically used as an anti-hypertensive, but more ...

Lofexidine versus clonidine in rapid opiate detoxification.


J Subst Abuse Treat. 2001 Jul;21(1):11-7. Lofexidine versus clonidine in rapid opiate detoxification. Gerra G(1), Zaimovic A, Giusti F, Di Gennaro C, Zambelli U,  ...

Evidence-Based Addiction Medicine


Is there any evidence that lofexidine is as effective as and better tolerated than clonidine for opiate detoxification? Could lofexidine be safely combined with ...

Lofexidine tablets | Patient


Lofexidine tablets are used to replace opiates when the usage of opiods is trying to be reduced.

Clonidine, lofexidine and similar medications for the management of ...


Mar 31, 2014 ... Review question. We reviewed the evidence about the effect of alpha2- adrenergic agonists (clonidine, lofexidine, guanfacine and tizanidine) in ...

Lofexidine (Subutex, Buprenorphine, Britoflex, Naltraxone) | Ascert


Lofexidine (Subutex, Buprenorphine, Britoflex, Naltraxone). Lofexidine SCIENTIFIC TERM: 17-(cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy- 18 ...

BritLofex Tablets 0.2mg - Summary of Product Characteristics (SPC ...


Oct 8, 2015 ... The dosage of lofexidine should be titrated according to the patient's response. Initial dosage should be 0.8mg per day in divided doses.

Lofexidine - Drugs Forum


Apr 12, 2012 ... Lofexidine (Britlofex) is an alpha2-adrenergic receptor agonist commonly used to alleviate some of the physical symptoms of opiate withdrawal ...

DrugBank: Lofexidine


Oct 21, 2007 ... Lofexidine is an alpha2-adrenergic receptor agonist. It can be used as a short acting anti-hypertensive, but is mostly used to help relieve ...

Guidance For NHS Grampian Staff For The Use Of Lofexidine In The ...


Guidance, lofexidine, opioid, opiate, symptomatic, withdrawal. Process Document : Policy,. Protocol, Procedure or. Guideline. Guidance. Document application:.

Popular Q&A
Q: What is lofexidine?
A: Lofexidine is an alpha2-adrenergic receptor agonist, most commonly used to alleviate physical symptoms of heroin and opiate withdrawal. report this answer. Upda... Read More »
Source: www.kgbanswers.co.uk
Q: How to take lofexidine
A: Lofexidine may be used as part of a detoxification programme in hospital or at home. Because each programme is tailored to meet a person's individual needs and ... Read More »
Source: www.patient.co.uk
Q: How should lofexidine be prescribed for detoxification?
A: Lofexidine needs to be monitored carefully. The blood pressure and pulse rate should be measured daily while the dose is increasing, so it may not be ideal for ... Read More »
Source: www.cks.nhs.uk
Q: How should lofexidine be prescribed for detoxification?
A: Lofexidine therapy is most likely to be successful in people who: Have shorter drug and treatment histories. Have made an informed and clinically appropriate de... Read More »
Source: www.cks.nhs.uk
Helpful Resources

US WorldMeds - Lofexidine Hydrochloride for treatment of opiate ...


Lofexidine is approved in the United Kingdom as BritLofex<sup>®</sup> and has been used in successful detoxification of more than 200,000 opiate addicts. US WorldMeds ...