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Nitisinone - Wikipedia


Nitisinone (INN), also known as NTBC is a medication used to slow the effects of hereditary tyrosinemia type 1. Since its first use for this indication in 1991, it has ...

Orfadin (Nitisinone Capsules and Oral Suspension): Side Effects ...


ORFADIN contains nitisinone, which is a hydroxyphenyl-pyruvate dioxygenase inhibitor indicated as an adjunct to dietary restriction of tyrosine and ...

Orfadin, INN-nitisinone - European Medicines Agency - Europa


nitisinone treatment, a diet deficient in phenylalanine and tyrosine is ... after the start of nitisinone treatment, the nitisinone dose should be increased to 1.5 mg/kg  ...

Orfadin, INN-Nitisinone - European Medicines Agency


Nitisinone or NTBC (2-(2- nitro-4-trifluoromethylbenzoyl)-1 ... nitisinone as a herbicide was discontinued, ongoing animal studies were halted and not reported, ...

FDA approves ORFADIN® (nitisinone) Oral Suspension


Apr 26, 2016 ... ORFADIN® (nitisinone) blocks the breakdown of tyrosine, thereby reducing the amount of toxic by-products in the body. In the most common ...

Use of nitisinone in patients with alkaptonuria.


Metabolism. 2005 Jun;54(6):719-28. Use of nitisinone in patients with alkaptonuria. Suwannarat P(1), O'Brien K, Perry MB, Sebring N, Bernardini I, ...

Nitisinone - DrugBank


Description, Nitisinone is a synthetic reversible inhibitor of 4- hydroxyphenylpyruvate dioxygenase. It is used in the treatment of hereditary tyrosinemia type 1.

Nitisinone ≥95% (HPLC) | Sigma-Aldrich


Sigma-Aldrich offers Sigma-SML0269, Nitisinone for your research needs. Find product specific information including CAS, MSDS, protocols and references.

Nitisinone - Side Effects, Dosage, Interactions | Everyday Health


Nov 5, 2014 ... Nitisinone works by preventing the body from breaking down an amino acid called tyrosine and by keeping other toxic substances from building ...

ORFADIN® capsules (nitisinone) DESCRIPTION Orfadin® capsules ...


Jan 18, 2002 ... Orfadin® capsules contain nitisinone, which is a synthetic reversible inhibitor of. 4-hydroxyphenylpyruvate dioxygenase used in the treatment of ...

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Orfadin (nitisinone) is the only FDA approved therapy, for use with dietary restriction of tyrosine and phenylalanine, for the treatment of tyrosinemia type 1.

nitisinone oral : Uses, Side Effects, Interactions, Pictures, Warnings ...


Find patient medical information for nitisinone oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

Nitisinone: Indications, Side Effects, Warnings - Drugs.com


Easy to read patient leaflet for nitisinone. Includes indications, proper use, special instructions, precautions, and possible side effects.