Nitisinone (INN), also known as NTBC is a medication used to slow the effects of
hereditary tyrosinemia type 1. Since its first use for this indication in 1991, it has ...
Orfadin (nitisinone) is the only FDA approved therapy, for use with dietary
restriction of tyrosine and phenylalanine, for the treatment of tyrosinemia type 1.
ORFADIN contains nitisinone, which is a hydroxyphenyl-pyruvate dioxygenase
inhibitor indicated as an adjunct to dietary restriction of tyrosine and ...
Easy to read patient leaflet for nitisinone. Includes indications, proper use,
special instructions, precautions, and possible side effects.
Find patient medical information for nitisinone oral on WebMD including its uses,
side effects and safety, interactions, pictures, warnings and user ratings.
Description, Nitisinone is a synthetic reversible inhibitor of 4-
hydroxyphenylpyruvate dioxygenase. It is used in the treatment of hereditary
tyrosinemia type 1.
nitisinone treatment, a diet deficient in phenylalanine and tyrosine is ... after the
start of nitisinone treatment, the nitisinone dose should be increased to 1.5 mg/kg
Metabolism. 2005 Jun;54(6):719-28. Use of nitisinone in patients with
alkaptonuria. Suwannarat P(1), O'Brien K, Perry MB, Sebring N, Bernardini I, ...
Orfadin® (nitisinone). Swedish Orphan Biovitrum has the worldwide rights to this
product. What is Orfadin? Orfadin is a hard white capsule for oral use.