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Vorinostat

en.wikipedia.org/wiki/Vorinostat

Vorinostat (rINN) also known as suberanilohydroxamic acid is a member of a larger class of compounds that inhibit histone deacetylases (HDAC).

DrugBank: Vorinostat

www.drugbank.ca/drugs/DB02546

Jun 13, 2005 ... Description. Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation for the treatment of cutaneous ...

Vorinostat - Chemotherapy Drugs - Chemocare

chemocare.com/chemotherapy/drug-info/Vorinostat.aspx

(vor-IN-o-stat). Trade Name: Zolinza. Drug Type: Vorinostat is an anti-cancer (" antineoplastic" or "cytotoxic") chemotherapy drug. Vorinostat is classified as an ...

Vorinostat | C14H20N2O3 - PubChem

pubchem.ncbi.nlm.nih.gov/compound/Vorinostat

Suberoylanilide Hydroxamic Acid is a synthetic hydroxamic acid derivative with antineoplastic activity. Vorinostat, a second generation polar-planar compound, ...

FDA Approval Summary: Vorinostat for Treatment of Advanced ...

theoncologist.alphamedpress.org/content/12/10/1247.full

Structure of vorinostat (suberoylanilide hydroxamic acid, SAHA). Phase I vorinostat clinical trials were initiated with both an i.v. and an oral drug formulation [2, 6, ...

Vorinostat: MedlinePlus Drug Information

medlineplus.gov/druginfo/meds/a607050.html

Vorinostat is used to treat cutaneous T-cell lymphoma (CTCL, a type of cancer) in people whose disease has not improved, has gotten worse, or has come back ...

Definition of vorinostat - NCI Drug Dictionary - National Cancer ...

www.cancer.gov/publications/dictionaries/cancer-drug?cdrid=37944

Vorinostat, a second generation polar-planar compound, binds to the catalytic domain of the histone deacetylases (HDACs). This allows the hydroxamic moiety  ...

Cancer biology: mechanism of antitumour action of vorinostat ...

www.nature.com/bjc/journal/v95/n1s/full/6603463a.html

Dec 12, 2006 ... Vorinostat (suberoylanilide hydroxamic acid or SAHA) is a nanomolar inhibitor of HDAC activity that has undergone initial evaluation in multiple ...

Zolinza (Vorinostat) Drug Information: Description, User Reviews ...

www.rxlist.com/zolinza-drug.htm

Learn about the prescription medication Zolinza (Vorinostat), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling.

Vorinostat (Zolinza®, suberoylanilide hydroxamic acid, SAHA ...

www.oncolink.org/treatment/article.cfm?c=143&id=379

Dec 10, 2015 ... Vorinostat is in a class of anti-cancer therapies called histone deacetylase ( HDAC) inhibitors. Histone deacetylation is a biochemical process ...

More Info

Zolinza - Merck

www.merck.com

Results of animal studies indicate that vorinostat crosses the placenta and is found in fetal plasma at levels up to 50% of maternal concentrations. Doses.

Vorinostat—An Overview - NCBI - National Institutes of Health

www.ncbi.nlm.nih.gov

Vorinostat is a new drug used in the management of cutaneous T cell lymphoma when the disease persists, gets worse or comes back during or after treatment ...

FDA Approval for Vorinostat - National Cancer Institute

www.cancer.gov

Jul 3, 2013 ... On October 6, 2006, the U.S. Food and Drug Administration granted approval to vorinostat (Zolinza™, Merck & Co., Inc.), a histone deacetylase ...