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Vorinostat

en.wikipedia.org/wiki/Vorinostat

Vorinostat (rINN) also known as suberanilohydroxamic acid is a member of a larger class of compounds that inhibit histone deacetylases (HDAC).

Zolinza - Merck

www.merck.com/product/usa/pi_circulars/z/zolinza/zolinza_pi.pdf

Results of animal studies indicate that vorinostat crosses the placenta and is found in fetal plasma at levels up to 50% of maternal concentrations. Doses.

Vorinostat: MedlinePlus Drug Information

www.nlm.nih.gov/medlineplus/druginfo/meds/a607050.html

Vorinostat is used to treat cutaneous T-cell lymphoma (CTCL, a type of cancer) in people whose disease has not improved, has gotten worse, or has come back ...

FDA Approval for Vorinostat - National Cancer Institute

www.cancer.gov/about-cancer/treatment/drugs/fda-vorinostat

Jul 3, 2013 ... On October 6, 2006, the U.S. Food and Drug Administration granted approval to vorinostat (Zolinza™, Merck & Co., Inc.), a histone deacetylase ...

Cancer biology: mechanism of antitumour action of vorinostat ...

www.nature.com/bjc/journal/v95/n1s/full/6603463a.html

Dec 12, 2006 ... The HDAC inhibitor vorinostat (suberoylanilide hydroxamic acid or SAHA) blocks cancer cell proliferation both in vitro and in vivo with little or ...

Vorinostat (Zolinza®, suberoylanilide hydroxamic acid, SAHA ...

www.oncolink.org/treatment/article.cfm?c=143&id=379

Dec 10, 2015 ... Vorinostat is in a class of anti-cancer therapies called histone deacetylase ( HDAC) inhibitors. Histone deacetylation is a biochemical process ...

FDA Approval Summary: Vorinostat for Treatment of Advanced ...

theoncologist.alphamedpress.org/content/12/10/1247.full

Structure of vorinostat (suberoylanilide hydroxamic acid, SAHA). Phase I vorinostat clinical trials were initiated with both an i.v. and an oral drug formulation [2, 6, ...

Zolinza (vorinostat) Uses, Dosage, Side Effects - Drugs.com

www.drugs.com/zolinza.html

Zolinza (vorinostat) is used to treat skin problems caused by cutaneous T-cell lymphoma. Zolinza is usually given after other treatments have been tried without  ...

Vorinostat: Indications, Side Effects, Warnings - Drugs.com

www.drugs.com/cdi/vorinostat.html

Easy to read patient leaflet for vorinostat. Includes indications, proper use, special instructions, precautions, and possible side effects.

SAHA (Vorinostat). - PAGEPress

www.pagepress.org/journals/index.php/hmr/article/download/724/828

Vorinostat (suberoylanilide hydroxamic acid; Zolinza®;. Merck; Whitehouse Station,. USA) also known as SAHA, is a competitive oral inhibitor. (HDAC-i) of Class ...

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Vorinostat - Chemotherapy Drugs - Chemocare

chemocare.com

(vor-IN-o-stat). Trade Name: Zolinza. Drug Type: Vorinostat is an anti-cancer (" antineoplastic" or "cytotoxic") chemotherapy drug. Vorinostat is classified as an ...

Zolinza (Vorinostat) Drug Information: Description, User Reviews ...

www.rxlist.com

Learn about the prescription medication Zolinza (Vorinostat), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling.

Vorinostat - National Cancer Institute

www.cancer.gov

Oct 10, 2006 ... This page contains brief information about vorinostat and a collection of links to more information about the use of this drug, research results, ...