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Vorinostat

en.wikipedia.org/wiki/Vorinostat

Vorinostat (rINN) also known as suberanilohydroxamic acid is a member of a larger class of compounds that inhibit histone deacetylases (HDAC).

Zolinza - Merck

www.merck.com/product/usa/pi_circulars/z/zolinza/zolinza_pi.pdf

Results of animal studies indicate that vorinostat crosses the placenta and is found in fetal plasma at levels up to 50% of maternal concentrations. Doses.

Vorinostat: MedlinePlus Drug Information

medlineplus.gov/druginfo/meds/a607050.html

Aug 15, 2016 ... Vorinostat is used to treat cutaneous T-cell lymphoma (CTCL, a type of cancer) in people whose disease has not improved, has gotten worse, ...

Vorinostat | C14H20N2O3 - PubChem

pubchem.ncbi.nlm.nih.gov/compound/Vorinostat

Suberoylanilide Hydroxamic Acid is a synthetic hydroxamic acid derivative with antineoplastic activity. Vorinostat, a second generation polar-planar compound, ...

SAHA ≥98% (HPLC) | Sigma-Aldrich

www.sigmaaldrich.com/catalog/product/sigma/sml0061?lang=en&region=US

SAHA or Vorinostat facilitates the transcription of genes that result in apoptosis, differentiation and growth arrest. It has been observed to give beneficial results ...

Vorinostat - National Cancer Institute

www.cancer.gov/about-cancer/treatment/drugs/vorinostat

Oct 10, 2006 ... This page contains brief information about vorinostat and a collection of links to more information about the use of this drug, research results, ...

FDA Approval for Vorinostat - National Cancer Institute

www.cancer.gov/about-cancer/treatment/drugs/fda-vorinostat

Jul 3, 2013 ... On October 6, 2006, the U.S. Food and Drug Administration granted approval to vorinostat (Zolinza™, Merck & Co., Inc.), a histone deacetylase ...

Cancer biology: mechanism of antitumour action of vorinostat ...

www.nature.com/bjc/journal/v95/n1s/full/6603463a.html

Dec 12, 2006 ... Vorinostat (suberoylanilide hydroxamic acid or SAHA) is a nanomolar inhibitor of HDAC activity that has undergone initial evaluation in multiple ...

Zolinza (Vorinostat): Side Effects, Interactions, Warning, Dosage ...

www.rxlist.com/zolinza-drug.htm

Vorinostat is a white to light orange powder. It is very slightly soluble in water, slightly soluble in ethanol, isopropanol and acetone, freely soluble in dimethyl ...

Vorinostat: A Novel Therapy for the Treatment of Cutaneous T-Cell ...

www.medscape.com/viewarticle/722524_3

Pharmacology. Vorinostat is a member of the hydroxamic acid subclass of histone deacetylase (HDAC) inhibitors. Its primary biochemical mechanism is to ...

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Vorinostat - Chemotherapy Drugs - Chemocare

chemocare.com

(vor-IN-o-stat). Trade Name: Zolinza. Drug Type: Vorinostat is an anti-cancer (" antineoplastic" or "cytotoxic") chemotherapy drug. Vorinostat is classified as an ...

Vorinostat—An Overview - NCBI - National Institutes of Health

www.ncbi.nlm.nih.gov

Vorinostat is a new drug used in the management of cutaneous T cell lymphoma when the disease persists, gets worse or comes back during or after treatment ...

Vorinostat (Zolinza®, Saha) | OncoLink

www.oncolink.org

Dec 10, 2015 ... Vorinostat is in a class of anti-cancer therapies called histone deacetylase ( HDAC) inhibitors. Histone deacetylation is a biochemical process ...