A gene knockout (abbreviation: KO) is a genetic technique in which one of an
organism's genes is made inoperative Also known as knockout organisms or ...
This is because knocking out a gene (as it is called) is important in so much of
biology. For example, if you type "knockout mouse" into PubMed (a search
Sep 4, 2013 ... Short animation explaining the basics of one step gene knockout. This is the most
widely used method to make knockout.
Nov 17, 2014 ... describing the principles of gene knockout and its application.
Permanent change in DNA leading to the loss of function of a gene, caused by a
manipulation of the organism's DNA in a laboratory followed by breeding to ...
medical-dictionary.thefreedictionary.com/Gene Knockout Technique
An experimental technique used in genetics in which a normal gene is replaced
by a defective gene either at the exact same chromosomal site—hence, the ...
A gene knock-out (KO) is a genetic technique supplemented with
biotechnological tool, in which an organism is engineered to carry genes that
have been made ...
copies of the mutated gene. These are what we commonly call “knockout mice”,
and these are the ones we. are most interested in studying. HOMOZYGOUS ...
Most commonly, the Cre-lox system  is utilized for conditional mutation of a
gene. Using a conditional knockout approach limits the risk of embryonic lethality
restricted gene knockout should allow a more precise tion but only in those cell
type(s) in which the Cre gene– associated promoter is active (Figure 1A).