Human genetic variation is the genetic differences both within and among
populations. There ... Causes of differences between individuals include the
exchange of genes during meiosis and various mut...
Gene flow tends to reduce diffences between populations.
Because genes are passed down from parents to offspring, diseases tend to ...
has greatly reduced the prevalence of this disease in the Ashkenazi population.
... Most of the genetic differences between human populations today appear to ...
Reduction or restriction of gene flow between populations is essential for the ...
Assortative mating occurs when individuals tend to mate with those that have the
... or out of a population can breakdown genetic differences between populations.
Small populations are generally at a greater risk of extinction than large ... The
rates at which genetic variability is added to a population by these two processes
differ ... As noted in the figure below, the mutation rate would have to be between
10X ... Reduction of genetic variability in a population can lead to any or all of the
Note that the level of genetic variation within a population is dynamic: It .... Figure
4: The relationship between Ne and Nf in a population of 1000 mating ... will
reduce Ne (the size of an ideal population that experiences genetic drift ...
Consider that, depending on the measure used, randomly chosen humans tend
to differ at ....
Genetic drift - "In small populations, chance events produce outcomes that differ
... Migration - "In an evolutionary sense, the movement of alleles between
populations" (p. ... If selection and migration tend to increase the frequencies of
the same ... is stronger than selection, differences among populations will be
DISCUSSIONS of genetic differences between major human populations have
long .... Pairs of individuals are classified as “within population” or “between .....
rate with the same data, far more loci would be needed to reduce equation M43 ...
They do not account for population differences within the species range ... 2007a)
, differences between leading and trailing edge populations (Hampe and Petit
2005), ... These sink populations tend to have higher mortality than local
recruitment .... compromised fitness and reduced genetic variation, especially if
We find a strong relationship between effective population size and the depth of
... we detect differences between 'healthy' individuals within populations for the ....
one (since sites with GERP < 1 tend to have no correlation with MAF and thus are
... see reduced overall MAF in the regions flanking genes in these population...