Trypsinogen (EC 18.104.22.168/20/21/23/24/26) is the precursor form or zymogen of
trypsin, a digestive enzyme. Produced by the pancreas, it is found in pancreatic ...
The premature activation of trypsinogen in the pancreatic interstitium, with the
subsequent activation of other pancreatic zymogens, is believed to lead to the ...
The exocrine pancreas synthesizes and secretes more protein per cell than any
other exocrine organ. Much of its protein secretion consists of digestive ...
During pancreatits, anionic trypsinogen becomes the predominant isoforms
secreted from the pancreas, and there is an increased level of zymogen in serum.
Pancreatic zymogens are normally only activated after they reach the small
intestine. A brush border enzyme, enterokinase, cleaves a peptide from
the inactive precursor of trypsin, secreted by the pancreas and activated to trypsin
by contact with enterokinase. Miller-Keane Encyclopedia and Dictionary of ...
Jun 10, 2014 ... A trypsinogen test sometimes is ordered when children or adults present with
symptoms suggesting cystic fibrosis and pancreatic dysfunction ...
Jun 18, 2015 ... Disorders of trypsin production can not only hinder digestive processes, they can
damage the pancreas. Trypsin production in tissues other ...
During acute pancreatitis, enzymes from your pancreas can escape into your
blood. One of these enzymes is trypsin. It's made from trypsinogen. Trypsinogen ...
Trypsin, produced in an inactive form by the pancreas, is remarkably similar in
chemical composition and in structure to the other chief pancreatic proteinase, ...