Domains are distinct functional and/or structural units in a protein. Usually they
are responsible for a particular function or interaction, contributing to the overall ...
Protein domains that have a necessary function are often used in many different
proteins. ... Protein domains often serve as structural units that define a protein.
Apr 6, 2013 ... There are also more complex motif models. Protein domains, on the other hand,
are a structural entity, usually meaning a part of the protein ...
Jun 12, 2012 ... We propose a thermodynamically-based definition in which a domain is a
segment of the folded protein for which the m-value in isolation and ...
May 20, 2009 ... (2) A part of protein that can fold, function and exist independently of the rest of
the protein chain or structure. Supplement. Protein domains vary ...
Curr Protoc Protein Sci. 2011 Nov;Chapter 2:Unit2.14. doi: 10.1002/0471140864.
ps0214s66. Protein structural domains: definition and prediction. Ezkurdia I(1) ...
Many protein molecules are composed of more than one subunit, where each ....
The above definition of domains, in which they are thought of as potentially ...
May 19, 2015 ... Protein domains are generally thought to correspond to units of evolution. New
research raises questions about how such domains are defined ...
As a result of these different paradigms, there still does not exist a precise
definition for a protein domain, nor do experts always agree on the number or
Such HMM profiles are used to define protein families in the Pfam database . In
many cases, these families consist of functional domains in larger proteins.