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What are protein domains? < Protein Classification < Introduction ...


Domains are distinct functional and/or structural units in a protein. Usually they are responsible for a particular function or interaction, contributing to the overall ...

Protein structural domains: definition and prediction. - NCBI


Curr Protoc Protein Sci. 2011 Nov;Chapter 2:Unit2.14. doi: 10.1002/0471140864. ps0214s66. Protein structural domains: definition and prediction. Ezkurdia I(1) ...

NCBI Conserved Domain Database (CDD) Help


What is CD-Search, and what information can it provide about a protein? .... We define conserved domains as recurring units in molecular evolution, the extents ...



Database of protein domains, families and functional sites. PROSITE consists of documentation entries describing protein domains, families and functional sites ...

Protein Domains & Interactions | Cell Signaling Technology


A categorical list of protein domain resources by Cell Signaling Technology. Each resource contains specific domain structure, function, and binding information.

A thermodynamic definition of protein domains


Jun 12, 2012 ... We propose a thermodynamically-based definition in which a domain is a segment of the folded protein for which the m-value in isolation and ...

Structure, function and evolution of multidomain proteins


Here, we define a protein domain as an inde- pendent, evolutionary unit that can form a single-domain protein or be part of one or more different multidomain.

Subunits and Domains: The Anatomy & Taxonomy of Protein Structure


Many protein molecules are composed of more than one subunit, where each .... The above definition of domains, in which they are thought of as potentially ...

Partial protein domains: evolutionary insights and bioinformatics ...


May 19, 2015 ... In discussing these articles, it must be emphasized that the definition of a protein domain is complex. One approach to define a protein domain ...

Clustering of protein domains for functional and evolutionary studies ...


Such HMM profiles are used to define protein families in the Pfam database [3]. In many cases, these families consist of functional domains in larger proteins.

Protein domain - Wikipedia
A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the ... More »
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Protein Domains, Domain Assignment, domain identification, the ...


Protein domains: Identification and assignment. ... such cases the easiest would be to consult the CATH database, which gives a clear definition of the domains.

Differences Between Protein Motifs and Protein Domains?


Apr 6, 2013 ... There are also more complex motif models. Protein domains, on the other hand, are a structural entity, usually meaning a part of the protein ...

Protein domain - Biology-Online Dictionary


May 20, 2009 ... (2) A part of protein that can fold, function and exist independently of the rest of the protein chain or structure. Supplement. Protein domains vary ...