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What are protein domains? < Protein Classification < Introduction ...

www.ebi.ac.uk/training/online/course/introduction-protein-classification-ebi/protein-classification/what-are-protein-domains

Domains are distinct functional and/or structural units in a protein. Usually they are responsible for a particular function or interaction, contributing to the overall ...

Multidomain Proteins - Encyclopedia of Life Sciences

www.els.net/WileyCDA/ElsArticle/refId-a0005053.html

Protein domains that have a necessary function are often used in many different proteins. ... Protein domains often serve as structural units that define a protein.

Differences Between Protein Motifs and Protein Domains? - Biology

biology.stackexchange.com/questions/7785/differences-between-protein-motifs-and-protein-domains

Apr 6, 2013 ... There are also more complex motif models. Protein domains, on the other hand, are a structural entity, usually meaning a part of the protein ...

A thermodynamic definition of protein domains

www.pnas.org/content/109/24/9420.full

Jun 12, 2012 ... We propose a thermodynamically-based definition in which a domain is a segment of the folded protein for which the m-value in isolation and ...

Protein domain - Biology-Online Dictionary

www.biology-online.org/dictionary/Protein_domain

May 20, 2009 ... (2) A part of protein that can fold, function and exist independently of the rest of the protein chain or structure. Supplement. Protein domains vary ...

Protein structural domains: definition and prediction. - NCBI

www.ncbi.nlm.nih.gov/pubmed/22045561

Curr Protoc Protein Sci. 2011 Nov;Chapter 2:Unit2.14. doi: 10.1002/0471140864. ps0214s66. Protein structural domains: definition and prediction. Ezkurdia I(1) ...

Subunits and Domains: The Anatomy & Taxonomy of Protein Structure

kinemage.biochem.duke.edu/teaching/anatax/html/anatax.2i.html

Many protein molecules are composed of more than one subunit, where each .... The above definition of domains, in which they are thought of as potentially ...

Partial protein domains: evolutionary insights and bioinformatics ...

genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0663-8

May 19, 2015 ... Protein domains are generally thought to correspond to units of evolution. New research raises questions about how such domains are defined ...

Identifying structural domains of proteins using clustering | BMC ...

bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-13-286

As a result of these different paradigms, there still does not exist a precise definition for a protein domain, nor do experts always agree on the number or location ...

Clustering of protein domains for functional and evolutionary studies ...

bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-10-335

Such HMM profiles are used to define protein families in the Pfam database [3]. In many cases, these families consist of functional domains in larger proteins.

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Protein domain
A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the ... More »
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Protein Domains, Domain Assignment, domain identification, the ...

www.proteinstructures.com

Certain protein domains have some clearly defined function associated with them , like the Rossmann-fold domain, also called coenzyme-binding domain, ...

Structure, function and evolution of multidomain proteins - MRC ...

www.mrc-lmb.cam.ac.uk

Here, we define a protein domain as an inde- pendent, evolutionary unit that can form a single-domain protein or be part of one or more different multidomain.

ExPASy - PROSITE

prosite.expasy.org

Database of protein domains, families and functional sites. PROSITE consists of documentation entries describing protein domains, families and functional sites ...