St. Paul the Apostle made four missionary journeys, all of which are detailed in the Book of Acts. The first three of these missionary journeys were essentially tours of various Near East and Baltic regions, while the fourth was St. Paul's journey to Rome.
Paul undertook his first missionary journey (Acts 13:4 - 15:35) with Barnabas. It followed Paul's conversion in Damascus to Christianity, before which he was known by the name Saul. Starting in Selucia, Antioch's seaport, the pair sailed for Cyprus. Here, they preached in synagogues and attempted to convert Jews. Their journey continued through Pamphylia, Pisidia and Lycaonia, preaching in Iconium, Lystra and Derbe, before making a return journey to Antioch via Attalia.
Eventually, Paul embarks on the second missionary journey (Acts 15:36 - 18:22) with Silas. This was another round trip from Antioch to many of the same destinations.
The third missionary journey (Acts 18:23 - 21:17) was to Galatia, Phrygia, Macedonia and Greece and crossed into Caesarea and Jerusalem.
In Caesarea, Paul was imprisoned by the Jews. His fourth journey (Acts 27:1 - 28:16) was to Rome under escort, during which he was shipwrecked. Upon reaching his destination, he was placed under house arrest.