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Dobutamine is a sympathomimetic drug used in the treatment of heart failure and cardiogenic shock. Its primary mechanism is direct stimulation of β1 receptors of the sympathetic nervous system. Dobutamine was developed in the 1970s by Drs . Ronald Tuttle and Jack Mills at Eli Lilly and Company, as a structural analogue ...


The clinical formulation is supplied in a sterile form for intravenous use only. Each mL contains: Dobutamine hydrochloride, equivalent to 12.5 mg (41.5 μmol) dobutamine; 0.24 mg sodium metabisulfite (added during manufacture), and water for injection. pH adjusted between 2.5 to 5.5 with hydrochloric acid and/or sodium ...


Medscape - Indication-specific dosing for (dobutamine), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.


Easy to read patient leaflet for Dobutamine. Includes indications, proper use, special instructions, precautions, and possible side effects.


Identification. Name: Dobutamine; Accession Number: DB00841 (APRD00122); Type: Small Molecule; Groups: Approved; Description. A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart ...


Class. synthetic isoprenaline derivative; adrenergic agonist; racemic mixture. Mechanism of Action. levo: alpha 1 agonist -> vasoconstriction + beta 2 effects -> inotropy; dextro: beta 1 and beta 2 agonist + alpha 1 blocking effects. -> inotropy with some vasodilation. Dose. 1-40mcg/kg/min, onset = minutes. Pharmaceutics.


The pharmacology of dobutamine. Ruffolo RR Jr(1). Author information: (1) Department of Pharmacology, Smith Kline & French Laboratories, Swedeland, Pennsylvania 19479. Dobutamine is a sympathomimetic amine that was designed as an inotropic agent for use in congestive heart failure. Clinically, dobutamine ...


Drug information on Dobutrex (dobutamine), includes drug pictures, side effects, drug interactions, directions for use, symptoms of overdose, and what to avoid.


Jul 21, 2016 ... Dobutamine - Get up-to-date information on Dobutamine side effects, uses, dosage, overdose, pregnancy, alcohol and more. Learn more about Dobutamine.