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en.wikipedia.org/wiki/Protamine_sulfate

Protamine sulfate is a medication that is used to reverse the effects of heparin. It is specifically used in heparin overdose, in low molecular weight heparin ...

en.wikipedia.org/wiki/Protamine

Protamines are small, arginine-rich, nuclear proteins that replace histones late in the haploid phase of spermatogenesis and are believed essential for sperm ...

www.rxlist.com/protamine-drug.htm

Learn about Protamine (Protamines) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications.

www.empr.com/protamine-sulfate/drug/2866

Fish allergy. Previous exposure to protamine (including insulin). Severe left ventricular dysfunction. Abnormal pulmonary hemodynamics. Previous vasectomy.

reference.medscape.com/drug/protamine-343746

Medscape - Indication-specific dosing for (protamine), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation ...

dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e1964129-33f4-4e4e-86e3-8e6a4e65bd83

Protamine sulfate can cause severe hypotension, cardiovascular collapse, noncardiogenic pulmonary edema, catastrophic pulmonary vasoconstriction, and  ...

www.ncbi.nlm.nih.gov/pubmed/2193773

The majority of vasectomized men develop antibodies against different sperm antigens, including protamine. Due to the fact that salmon protamine is used ...

www.drugbank.ca/drugs/DB09141

Sep 30, 2015 ... Protamine sulfate is a drug that reverses the anticoagulant effects of heparin by binding to it. It was originally isolated from the sperm of salmon ...

lifeinthefastlane.com/ccc/protamine

strongly basic protamine + strongly acid heparin -> forms stable salt -> removed by reticuloendothelial system. inhibits formation and activity of thromboplastin ...